Godskesen T, Nygren P, Nordin K, Hansson M, Kihlbom U (2013) Phase 1 clinical trials in end-stage cancer: patient understanding of trial premises and motives for participation. Support Care Cancer 21(11):3137–3142 View ArticleGodskesen, T., Nygren, P., Nordin, K., Hansson, M., &...
BackgroundIn cancer, phase 1 clinical trials on new drugs mostly involve patients with advanced disease that is unresponsive to standard therapy. The purpose of this study was to explore the difficult ethical problems related to patient information and motives for participation in such trials.MethodA...
Most new treatments are developed in clinical trials. Clinical trials are studies that evaluate the effectiveness of new drugs or treatment strategies. The development of more effective cancer treatments requires that new and innovative therapies be evaluated with cancer patients. Participation in a clini...
Objective To justify the role of patient-reported outcome scale for hypertension(Hyper-PRO) in clinical trials of new drug development,and to evaluate its ... LM Dong,QJ Liu,XY Liu - 《Chinese Remedies & Clinics》 被引量: 5发表: 2012年 Development of a patient reported experience measure ...
We propose a new design for phase I (or phase II) dose-ranging clinical trials aiming at determining a dose of an experimental treatment to satisfy safety (respectively efficacy) requirements, at treating a sufficiently large number of patients to estimate the toxicity (respectively failure) probabi...
Clinicaltrials.gov NCT00341250 展开 关键词: Research Report Double-Blind Studies Clinical Trials Children Malaria Prevention Vaccines Administration and Dosage Immunization Safety Developing Countries DOI: 10.1371/journal.pone.0001563 被引量: 113 年份: 2008 ...
stage IV colon cancer in clinical trials. These trials test new treatments to see if they are safe and if they work. They are often a way for people to try a new medicine that isn't available to everyone. Your doctor can tell you if one of these trials might be a good fit for ...
1. Clinicaltrials.gov. A Study of TNB-486 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma. Available at https://clinicaltrials.gov/ct2/show/NCT04594642. Accessed 27 June 2022.
Pancreatic Cancer Clinical Trials help determine new treatments that could be beneficial to future and current patients. By participating in a clinical
1 nonrandomized clinical trial, immunization with the 100-μg dose of the ERBB2 ICD plasmid-based vaccine was associated with generation of ERBB2-specific type 1 T cells in most patients with ERBB2-expressing breast cancer, and it is currently being evaluated in randomized phase 2 trials. ...