百度试题 题目Ⅰ期临床试验(Phase I clinical trial) 相关知识点: 试题来源: 解析 观察人体对新药耐受程度、药代动力学,为制定给药方案提供依据,单次给药耐受性试验、单次给药及连续给药药代动力学试验; 反馈 收藏
clinicaladj. 1.(仅用于名词前)门诊的,临床的 2.医院的,诊所的 3.冷静客观的,不偏不倚的 4.(建筑物或房间)简朴干净的 trialn.[C] 1.[U,C](法院的)审讯,审理,审判 2.[C,U](对能力、质量、性能等的)试验,试用 3.麻烦;艰苦;痛苦;磨难,考验,磨练 4.惹麻烦的人(或东西),令人讨厌的人(或东 ...
1. 期临床试验 而Ⅰ期临床试验(Phase I clinical trial)是指初步的临床药理学及人体安全性评价试验。观察人体对新药的耐受程度和药代动力 … www.39kf.com|基于12个网页 2. 临床一期试验 ...体外培养的自体间叶系干细胞的安全性得到证实,这也是临床一期试验(phase I clinical trial)最重要的地方。
1. To support itsphase I clinical pharmacokinetic study, a sensitive and specific liquid chromatographic-tandem mass spectrometric assay was developed and validated for simultaneous quantification of imrecoxib and hydroxyimrecoxib in human seru. 为进行艾瑞昔布I期临床药代动力学研究,建立同时测定人血清中艾瑞...
1. Thefirststrip mini - mill in China; 中国第一座短流程薄板厂 2. The clinical study of freestyle positions on delivery during thefirstlabor strage; 分娩第一产程自由体位的临床研究 3. Clinical obstration on promoting thefirststage of the multigravidae by using of 654-2; ...
1. Methods: The phase Ⅲ clinical trial was conducted in 510 patients with chronic bronchitis. 方法:本试验为Ⅲ期临床试验,随机选取510例慢性支气管炎迁延期的患者,从咳嗽、咳痰、喘息、肺部哮鸣音、肺功能、肺部X线征象等方面观察治疗前后的变化,进行统计学处理,并考察其安全性。 更多例句>> 5...
clinical trial results a phase i study of the safety and pharmacokinetics of higher-dose icotinib in patients with advanced non-small cell lung cancer author summary lessons learnedThis phase I study evaluated the maximum tolerated dose, dose-limiting toxicities, safety, pharmacokinetics, and efficacy...
forthestudyofwhethersuchtoxicityisreversible 3)toidentifysafetyparametersforclinical monitoring 7 CoreToxicityEvaluation(1) •Forsingle-dosephaseIandrepeat-dose phaseIstudiesofupto14daysduration: –ADME/toxicokineticsinrodentandnon-rodent animalspecies –Safetypharmacology(cardiovascular,CNS, respiratory–ICHS7...
2011, Vol.54, No.4 21 202 學術 表1 各臨床試驗期別定義以及目標 期別 目標與特色 第一期 (phase I) ●首次應用於人體的試驗(first-in human study) ●屬於人體藥理學研究 ●受試者可以是健康受試者 ,或是特定疾病族群 ●受試者人數一般在30人以下 ●包括以下研究 - 藥物動力學 - 藥物效力學 - ...
BackgroundIn cancer, phase 1 clinical trials on new drugs mostly involve patients with advanced disease that is unresponsive to standard therapy. The purpose of this study was to explore the difficult ethical problems related to patient information and motives for participation in such trials.MethodA...