半定量RT-PCR验证了9个AS事件,包括7个外显子跳跃和2个外显子包含事件(图1D,E)。此外,还对RNA测序中的差异表达基因(DEGs)进行分析,GO发现RNA splicing是最显著下调的生物学过程。其反映在SR家族蛋白(SRSF1, SRSF3, SRSF6, SRSF7 and SRSF8)...
半定量RT-PCR验证了9个AS事件,包括7个外显子跳跃和2个外显子包含事件(图1D,E)。此外,还对RNA测序中的差异表达基因(DEGs)进行分析,GO发现RNA splicing是最显著下调的生物学过程。其反映在SR家族蛋白(SRSF1, SRSF3, SRSF6, SRSF7 and SRSF8)的水平显著下调。RT–qPCR证实SRSF3,SRSF6,SRSF7的表达在低氧组...
Splicing factor SRSF6 promotes hyperplasia of sensitized skin [J]. Nat Struct Mol Biol, 2014,21( 2) : 189-197Jensen MA, Wilkinson JE, Krainer AR. Splicing factor SRSF6 promotes hyperplasia of sensitized skin. Nat Struct Mol Biol. 2014; 21: 189-97. doi: 10.1038/nsmb.2756....
Alternative mRNA splicing of the smooth muscle myosin heavy chain (myh11) gene produces four different isoforms, one of which (SMB) is characterized by the inclusion of the exon5b, which doubles the smooth muscle cells contraction velocity. Deciphering the regulation of the expression levels of ...
Abnormal alternative splicing (AS) caused by alterations in spliceosomal factors is implicated in cancers. Standard models posit that splice site selection is mainly determined by early spliceosomal U1 and U2 snRNPs. Whether and how other mid/late-acting
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative ...
Gene SummaryThe protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. ...
hepatic steatosis nonalcoholic fatty liver disease RNA alternative splicing mitochondrial function mtDNA Drak2 serine/arginine-rich splicing factor (SRSF) Introduction In recent years, with the increasing consumption of energy-dense diets and sedentary lifestyles, NAFLD has become one of the most common...
Wan L, Yu W, Shen E, et al. SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer[J]. Gut, 2017:gutjnl-2017-314983. 联系我们 地址:武汉市东湖高新技术开发区高新大道666 号光谷生物城C1 栋2 层 ...
英文名称: Anti-SRSF6 Antibody (Clone#27S70) 产品规格: 50μl|100μl|150μl 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 抗体名称Anti-SRSF6 Antibody (Clone#27S70) 指标别名B52;FLJ08061;Pre mRNA splicing factor SRP55;SFRS6;SRP55;SRSF6;SR protein repeat...