SREBP1(a) Short Introduction In mammals, two isoforms of SREBP1 protein, SREBP1a and SREBP1c, are known, which arise by the use of two alternative first exons (both transcripts produced from the sameSREBF1 genethrough the use of alternate promoters). Exon 1a encodes the unique 29 amino ...
SREBP2 downregulates ABCA1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism ATP-binding cassette transporter-1 (ABCA1) is a pivotal regulator of cholesterol efflux from cells to apolipoproteins, whereas sterol responsive element bi... X Wang,MB Stemerman,Y...
产品名称 人固醇调节元件结合蛋白-1C(SREBP-1C) 货号 YXY-sw16348 价格说明 价格:商品在爱采购的展示标价,具体的成交价格可能因商品参加活动等情况发生变化,也可能随着购买数量不同或所选规格不同而发生变化,如用户与商家线下达成协议,以线下协议的结算价格为准,如用户在爱采购上完成线上购买,则最终以订单结算...
Their livers expressed no functional SREBP-1. There was a 1.5-fold upregulation of SREBP-2 at the level of mRNA and a two- to threefold increase in the amount of mature SREBP-2 in liver nuclei. Previous studies showed that SREBP-2 is much more potent than SREBP-1c, the predominant ...
爱企查为您提供人固醇调节元件结合蛋白-1C(SREBP-1C)可寄样本,上海亿芯源生物技术有限公司售卖商品,可电话联系商家或留言询价。调节元件;调节元件批发;调节元件行情报价;调节元件价格;调节元件底价;调节元件图片;调节元件厂家;调节元件生产厂家;调节元件品牌;调
Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) is regulated by SREBP‐1 and plays a role in fatty acid synthesis in caprine mammary epithelial c... Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in ...
2. 营养状态 srebp1的表达也受到营养状态的调控。高碳水化合物饮食会刺激srebp1的表达,从而增加脂肪酸和甘油三酯的合成。此外,胰岛素和葡萄糖也能够通过多种机制调节srebp1基因的转录活性。 3. 转录因子 除了上述调控途径外,srebp1的表达还受到多种转录因子的参与。其中,SREBP-1c自身也能够通过正向反馈机制增加其自身...
(mSREBP).b–dWestern analysis of SREBP-1 (full-length and mature) and pMEK (Ser217/221). GAPDH is used as a loading control.bWestern blot analysis for mSREBP levels in response to vemurafenib treatment in sensitive and resistant cells.cWestern blot analysis of BRAF wild-type (but NRAS ...
数据分析结果显示,脂质代谢受损和慢性炎症相关基因的上调与衰老过程中肝功能下降显著相关。特别地,甾醇调节元件结合蛋白(SREBP)及其下游信号传导的激活被认为是肝脏衰老的标志。这一发现扩展了我们对灵长类动物肝脏衰老的认识,并为进一步研究肝脏...
A-FABP(脂肪细胞型脂肪酸结合蛋白)和SREBP1(固醇调节元件结合蛋白)是动物体内参与脂肪沉积和脂质合成的重要基因.为了研究这两种基因在牛组织中的表达规律,研究利用qRT-PCR技术检测A-FABP和SREBP1在荷斯坦牛13种组织中表达水平,并进一步比较了这两个基因在秦川牛和雪龙黑牛脂肪,肌肉和肝脏的组织中表达差异.研究结果表明...