Interestingly, ZCCHC8 has also been shown to interact with the cap-binding complex (CBC) and several members of the SR protein family21, and one study has reported that, in vitro, RBM7 interacts with the splicing factor 3b subunit 2 (SAP145) and the SRSF3 protein26. The interaction ...
Hou et al., reported that the mutations in the splicing factor 3B subunit 1 (SF3B1), U2 small nuclear RNA auxiliary factor 2 (U2AF1), and serine and arginine rich splicing factor 2 (SRSF2), had an independent role in disease progression (Hou et al., 2016). Abnormal expression or ...
Splicing factor 3b subunit 4 (SF3B4) is a major subunit of the SF3B complex, consisting of two N-terminal RRMs and a C-terminal proline-rich (PR) domain (Fig.3D) [177]. In addition to its role in pre-mRNA splicing, SF3B4 is implicated in cell signaling, transcription, and translati...
产品名称 Rabbit anti-human splicing factor 3a, subunit 3, 60kDa polyclonal Antibody 产品货号 MBS712571 产品价格 现货询价,电话:010-67529703 产品规格 0,05 mL 产品品牌 MyBioSource 产品概述 [[ 其他大小:请联系我们订购其他不同大小的。[说明:此抗体需要在+4°C的冰箱中短期浓缩保存。冻融会破坏细胞...
On the basis of the structure, we identify a proline-rich segment within the splicing factor SAP145 with strong similarity to ZCCHC8. We show that this segment of SAP145 not only binds the RRM region of another splicing factor SAP49 but also the RRM of RBM7. These dual interactions of...
英文别名: SF3A3 (Splicing Factor 3A Subunit 3, PRP9, PRPF9, SF3a60, Spliceosome-associated Protein 61, SAP 61, SAP61) 中文名: 中文别名: CBNumber: CB35222781 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 SF3A3 (Splicing Factor 3A Subunit 3, PRP9, ...
Human splicing factor SF3a is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP) and its three subunits of 60, 66, and 120 kDa are essential for splicing in vitro and in vivo. The SF3a heterotrimer forms in the cytoplasm and enters the nucleus independently of ...
Amplification and detection of the candidate genes and of three reference genes (Splicing factor 3a, subunit 1 (SF3A1), Proteasome 26S subunit ATPase 4 (PSMC4), Pumilio homolog 1 (PUM1)) were conducted with a Realplex 2 Master Cycler (Eppendorf, Mississauga, Canada). We investigated the ...
Splicing factor 3b, subunit 1 SRSF2: Serine/arginine-rich splicing factor 2 U2AF1: U2 small nuclear RNA auxiliary factor 1 BCL-2: B cell lymphoma 2 IAP: Inhibitor of apoptosis BIM: Bcl-2-like protein 11 SRSF1: Serine/arginine-rich splicing factor 1 mTORC1: Mammalian target of...
A. et al. Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol. Cell 23, 49–59 (2006). Article CAS PubMed PubMed Central Google Scholar Lin, P. C. & Xu, R. M. Structure and assembly of the SF3a splicing factor complex of U2...