Alecensa effective against specific type of lung cancerRoche
Most cancer driver genes are involved in generic cellular processes such as DNA repair, cell proliferation and cell adhesion, yet their mutations are often confined to specific cancer types. To resolve this paradox, we explained mutation frequencies of selected genes across tumor types with four feat...
Lung cancer is the leading cause of cancer deaths worldwide1. Non-small cell lung cancer (NSCLC) represents the major histological type of lung malignancy diagnosed2. Lung adenocarcinoma (LUAD) is the most common histological subtype of NSCLC accounting for over 50% of diagnosed lung cancer case...
Molecular Insight in Gastric Cancer Induction: An Overview of Cancer Stemness Genes Gastric cancer is one of the most outgoing human cancers in the world. Two main functional types were described: Intestinal adenocarcinoma and diffuse one... H Akhavan-Niaki,AA Samadani - 《Cell Biochemistry & ...
African ancestry is a significant risk factor for advanced prostate cancer (PCa). Mortality rates in sub-Saharan Africa are 2.5-fold greater than global averages. However, the region has largely been excluded from the benefits of whole genome interrogati
We aimed to assess the type-specific HR-HPV viral load as a risk triage indicator for development of high-grade squamous intraepithelial lesion or worse (≥HSIL).A total of 19,446 women who underwent primary screening for cervical cancer using Cervista® HR-HPV and cytology assays were enroll...
The type-specific prevalence of high-risk HPV types significantly varies according to cervical cytology and age. It may imply that these types have different to develop into precancerous lesions in normal cervix. 展开 关键词: Age Cervical cytology HPV Prevalence ...
- 《Cancer Research》 被引量: 0发表: 2009年 The detection of virology in tear and clinical features of herpes keratitis Objective To evaluate the viral etiology test results, clinical features and treatment of patients who were diagnosed as herpes virus keratitis in clinic. Design A retrospective...
This analysis also found more fungal reads in all cancer types than in negative controls (Data S1.1D). In the TCGA cohort, we observed significant, cancer type-specific differences in the percentage of classified fungal, bacterial, and pan-microbial reads of the total or unmapped reads (Data ...
Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states; however, it remains unclear to what extent these states span tumor types, constituting general features of cancer. Here, we perform a pan-ca...