et al. SRSF2 is essential for hematopoiesis, and its myelodysplastic syndrome-related mutations dysregulate alternative pre-mRNA splicing. Mol. Cell. Biol. 35, 3071–3082 (2015). CAS PubMed PubMed Central Google Scholar Palangat, M. et al. The splicing factor U2AF1 contributes to cancer ...
Distinct functions of neutrophil in cancer and its regulation. Mediators Inflamm. 2015, 701067 (2015). PubMed PubMed Central Google Scholar Tecchio, C., Scapini, P., Pizzolo, G. & Cassatella, M. A. On the cytokines produced by human neutrophils in tumors. Semin. Cancer Biol. 23, 159...
Molecular Cancer is delighted to announce its new thematic series: mRNA therapies and mRNA vaccines in cancer Click here to access all thematic series published to date in Molecular Cancer. Featured Article: Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in...
Tumour types can be identified accurately according to the patterns of genetic changes seen throughout the genome, potentially aiding the diagnosis of a patient's cancer where conventional clinical tests could not identify its type, and knowledge of the exact tumour type could also help tailor treat...
Researchers discovered that some cancers grouped together based on the cell type from which the tumor came from. For example, squamous cell cancers from the head and neck, lung, and bladder, cervix, and esophagus had strong molecular similarities and grouped together. ...
Its formulation aims to stabilize blood sugar, providing relief to individuals dealing with diabetes or those striving to maintain healthy glucose levels. Beyond its primary function, Sugar Defender’s composition and mechanisms prompt exploration into its potential implications for other health concerns, ...
fibroblasts showed high expression of chemokines (CCL11, CXCL12, and CXCL14) (Fig.2b; Table S4), similar to the previously reported iCAFs in various types of tumors such as BC [6] and PTC [8]. GO enrichment analysis of its marker genes showed their association with the response to ...
In GBM, seliciclib and its next-generation derivative CYC065 (high-affinity for CDK2/5/9) restored apoptosis in human GBM cells and neurospheres. Seliciclib induced TRAIL-mediated apoptosis and suppressed survivin, XIAP, MCL1, and Cyclin E [67,68,69, 81]. Effects improved in combination ...
Support info of Expression Changes of Sex Hormone Binding Globulin in GDM Placental Tissue and Its Significance The objective was to examine prospectively the association between low testosterone and sex hormone-binding globulin (SHBG) levels and the subsequent development of type 2 diabetes in men.#...
Ductal metaplasia of human exocrine pancreas and its association with carcinoma.Cancer Res 1985; 45: 1285–1290. PubMed CAS Google Scholar Glenner G, Mallory GK. The cystadenoma and related nonfunctional tumors of the pancreas. Pathogenesis, classification, and significance.Cancer 1956; 9: 980–...