Potassium channels activated by sodium. Quart. J. Exp. Physiol. 74:1033-1041.MIARTIN. A. R. & DRYER, S. E. (1990). Potassium channels activated by sodium. Quarterly Journal of Experimental Physiology 74, 1033-1
Impact of a Terahertz electromagnetic field on the ion permeation of potassium and sodium channels Terahertz (THz) electromagnetic fields can alter ion channel conductance, however, the mechanism by which they do so is not fully understood. Here, the authors perform molecular dynamics simulations to ...
In all cases, calcium (Ca2+) influx and potassium (K+) efflux are key conductances that underlie the generation of MSMC action potentials [3, 4, 5,6•]. Specifically, Ca2+ influx causes both depolarization and electromechanical coupling [2,5,6•,7,8], as a high intracellular Ca2+ ...
L. Voltage-gated sodium channels: structure, function, pharmacology, and clinical indications. J. Med. Chem. 58, 7093–7118 (2015). Article PubMed Google Scholar Hodgkin, A. L. & Huxley, A. F. Currents carried by sodium and potassium ions through the membrane of the giant axon of ...
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et al. Voltage-gated potassium channel KCNV2 (Kv8.2) contributes to epilepsy susceptibility. Proc. Natl Acad. Sci. USA 108, 5443–5448 (2011). PubMed PubMed Central Google Scholar Mishra, V. et al. Scn2a deletion improves survival and brain-heart dynamics in the Kcna1-null mouse model...
3.1.2 Voltage-gated potassium channels Voltage-gated potassium channels (KV) are pore-forming membrane proteins that permit the efflux of potassium ions across cell membranes, influencing action potential threshold, waveform and frequency. As such, numerous species have evolved toxins that target KV ch...
triggers the opening of more sodium channels, further depolarizing the membrane potential. Within milliseconds, the sodium channels transition to an ion-impermeable inactivated state, while potassium channels are activated. Both events contribute to the restoration of the resting membrane potential [22]....
Sodium channels in normal and pathological pain. Annu Rev Neurosci. 2010;33:325–47. Article CAS PubMed Google Scholar Fan N, Donnelly DF, LaMotte RH. Chronic compression of mouse dorsal root ganglion alters voltage-gated sodium and potassium currents in medium-sized dorsal root ganglion ...
Sensors of intracellular sodium concentration exist such as the sodium-dependent potassium channels Slack and Slick (for a review see [81]). If one postulates that cytosolic calcium concentration is increased by the reverse functioning of NCX, which occurs when the membrane potential is more depolar...