Srinivasan, Y., Elmer, L., Davis, J., Benett, V., and Angelides, K. (1988). Ankyrin and spectrin associate with voltage-dependent so- dium channels in brain. Nature 333, 177-180.Srinivasan, Y., L. Elmer, J. Davis, V. Bennett, and K. Angelides. Ankyrin and spectrin associate ...
Voltage-gated Na+channels in the brain are complexes of a 260-kD α-subunit in association with auxiliary β-subunits (β1–β4) of 33–36kD.6Theα subunitcontains the voltage sensors and the ion-conducting pore in four internally repeated domains (I–IV), which each consists of six α...
COMPARISON OF PENTOBARBITAL EFFECTS ON HUMAN SODIUM CHANNELS FROM BRAIN, HEART AND STRIATED MUSCLE 来自 Semantic Scholar 喜欢 0 阅读量: 22 作者:HC Wartenberg,BW Urban 摘要: An abstract is unavailable.关键词: pulmonary embolism ambulance cardiopulmonary resuscitation thrombolytic therapy tissue-type ...
K ATP Channels in Cardiovascular System. ATP-sensitive K + (K ATP ) channels are inhibited by intracellular ATP and activated by intracellular nucleoside d... S Isomoto,KMD Yoshihisa,Y Kurachi - 《J Cardiovasc Electrophysiol》 被引量: 151发表: 1997年 Central role of the BK channel in urinar...
第一节离子通道概论(一)钠通道钠通道(sodium channels)是选择性允许Na+ 跨膜通过的离子通道。目前对钠通道特征、门控动 … www.taodocs.com|基于46个网页 2. 钠离子通道 中国医药大学 课程查询系统 ... 期中考 mid-exam钠离子通道Sodium channels钙离子通道 Calcium channels ... ...
1.Role of sodium channel in the neuroprotective effect induced by preconditioning with isoflurane in rats;钠离子通道在异氟醚预处理诱导的脑保护中的作用 2.Advances in research of fluvalinate resistance in Varroa destructor: sodium channels involved.;钠离子通道与蜜蜂狄斯瓦螨对氟胺氰菊酯的抗性机理 英文短...
Alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptors (AMPARs) are ion channels that mediate excitatory synaptic transmission in the brain. In rat neurons, NEDD4 was shown to ubiquitinate the AMPAR GLUR1 subunit, leading to lower levels of AMPAR at the cell surface, and a ...
Background—Arrhythmias associated with QT prolongation on the ECG often lead to sudden unexpected death in epilepsy. The mechanism causing a prolongation of the QT interval during epilepsy remains unknown. Based on observations showing an upregulation of neuronal sodium channels in the brain during ep...
Presents information on a study which described the potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL. Middle cerebral artery occlusion in the mouse; High affinity and specificity of binding BIII 890 CL to sodium channels; Materials and methods of the...
靶点 GABA receptor x Sodium channels 作用机制 GABA receptor激动剂(γ-氨基丁酸受体激动剂)、钠通道阻滞剂 治疗领域 神经系统疾病其他疾病 在研适应症 躁郁症偏头痛癫痫的复杂部分性发作+ [2] 非在研适应症 酒精相关疾病酗酒躁郁症1型+ [3] 原研机构 Abbott Laboratories 在研机构 AbbVie, Inc.Abbott Labora...