After intracerebroventricular infusion of aldosterone, the MAP, RSNA, and HR responses to intracerebroventricular infusion of aCSF containing 0.16 M Na[sup +] were blocked by blockade of brain OLC with intracerebroventricular infusion of Fab fragments or of brain sodium channels with intracerebro...
The segregation of voltage-dependent sodium channels to specialized regions of the neuron is crucial for propagation of an action potential. Studies of their lateral mobility indicate that sodium channels are freely mobile on the neuronal cell body but are immobile at the axon hillock, presynaptic te...
1.Role of sodium channel in the neuroprotective effect induced by preconditioning with isoflurane in rats;钠离子通道在异氟醚预处理诱导的脑保护中的作用 2.Advances in research of fluvalinate resistance in Varroa destructor: sodium channels involved.;钠离子通道与蜜蜂狄斯瓦螨对氟胺氰菊酯的抗性机理 英文短...
Background—Arrhythmias associated with QT prolongation on the ECG often lead to sudden unexpected death in epilepsy. The mechanism causing a prolongation of the QT interval during epilepsy remains unknown. Based on observations showing an upregulation of neuronal sodium channels in the brain during ep...
第一节离子通道概论(一)钠通道钠通道(sodium channels)是选择性允许Na+ 跨膜通过的离子通道。目前对钠通道特征、门控动 … www.taodocs.com|基于46个网页 2. 钠离子通道 中国医药大学 课程查询系统 ... 期中考 mid-exam钠离子通道Sodium channels钙离子通道 Calcium channels ... ...
Voltage-gated sodium channels in the mammalian heart Mammalian species express nine functional voltage-gated Na(+) channels. Three of them, the cardiac-specific isoform Nav1.5 and the neuronal isoforms Nav1.8 and Nav1.9, are relatively resistant to the neurotoxin tetrodotoxin (TTX; IC50 1 ... T...
Molecular properties of brain sodium channels: an important target for anticonvulsant drugs. The voltage-gated sodium channels that are responsible for action potential generation in central neurons are important targets for the actions of antiepil... CATTERALL,WA. - 《Advances in Neurology》 被引量...
COMPARISON OF PENTOBARBITAL EFFECTS ON HUMAN SODIUM CHANNELS FROM BRAIN, HEART AND STRIATED MUSCLE 来自 Semantic Scholar 喜欢 0 阅读量: 21 作者:HC Wartenberg,BW Urban 摘要: An abstract is unavailable.关键词: pulmonary embolism ambulance cardiopulmonary resuscitation thrombolytic therapy tissue-type ...
L. The role of non-pore-forming beta subunits in physiology and pathophysiology of voltage-gated sodium channels. Handb. Exp. Pharmacol. 221, 51–89 (2014). CAS PubMed Google Scholar Whitaker, W. R. et al. Comparative distribution of voltage-gated sodium channel proteins in human brain....
靶点 GABA receptor x Sodium channels 作用机制 GABA receptor激动剂(γ-氨基丁酸受体激动剂)、钠通道阻滞剂 治疗领域 神经系统疾病其他疾病 在研适应症 躁郁症偏头痛癫痫的复杂部分性发作+ [2] 非在研适应症 酒精相关疾病酗酒躁郁症1型+ [3] 原研机构 Abbott Laboratories 在研机构 AbbVie, Inc.浙江华海药业...