neurons - gating charge - sodium channels - caffeineUsing a voltage-clamp technique and intracellular dialysis, gating currents of sodium channels were first recorded and studied in neurons of the rat trigeminal ganglia. The rising phase of gating currents lasted 30 to 70 sec; these currents ...
A. Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons. Neuron 3, 695–704 (1989). CAS PubMed Google Scholar Jenkins, S. M. & Bennett, V. Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and...
176 STUDY OF IONIC SODIUM CHANNELS IN NEURONS FROM DORSAL ROOT GANGLIA SLICES MAINTAINED IN CULTURE176 study of ionic sodium channels in neurons from dorsal root ganglia slices maintained in culturedoi:10.1016/S1090-3801(06)60179-1N. Pascu...
Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus. Int J Dev Neurosci 14: 749 -760, 1996.w39x J. Stoll, Z. Galdzicki, Reduced expression of voltage-gated sodium channels in neurons cultured from trisomy 16 mouse hippocampus, Int. J. ...
Recent findings suggest that NALCN, in association with UNC79 and UNC80, contributes a basal Na + leak conductance in neurons. Mutations in Nalcn, Unc79, or Unc80 lead to severe phenotypes that include neonatal lethality and disruption in rhythmic behaviors. This review discusses the properties ...
Tetrodotoxin-resistant sodium channels in sensory neurons generate slow resurgent currents that are enhanced by inflammatory mediators. J Neurosci 2014;34:7190-... ZY Tan,AD Piekarz,BT Priest,... - 《Journal of Neuroscience the Official Journal of the Society for Neuroscience》 被引量: 0发表: ...
Sodium channels are important for generating electrical signals in neurons. Latest Research and Reviews Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6 Luis Manuel Arratia Juan David Bermudes-Contreras Absalom Zamorano-Carrillo ResearchOpen ...
TNF-alpha enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury. Chen X; Pang RP; Shen KF;.TNF-alpha enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury....
Sensory neurons in the dorsal root ganglia (DRG) express a subset of voltage dependent sodium channels (NaV) including NaV1.1, 1.6, 1.7, 1.8 and 1.9. Previous work supported preferential localization of NaV1.8 channels to small-medium diameter, nociceptive afferent neurons. However, we recently pu...
This phenomenon subsedes with maturation, but can be reinvoked when these animals receive sodium channel blockers such as lamotrigine, suggesting a dysfunction of striatal sodium channels. Voltage-gated fast sodium currents (INa+) were studied in acutely isolated striatal neurons from healthy and dts...