摘要：目的探讨长链非编码（lncRNA ）核仁小RNA 宿主基因15（SNHG15）靶向调节微小RNA -141（miR -141）对甲状腺癌细 胞侵袭、凋亡影响及机制。方法 本研究起止时间为2018年10月至2019年5月，参照Lipofectamine 2000说明将SNHG15小干扰RNA （siRNA ）、siRNA 阴性对照（siRNA control ）、miR -141抑制剂（miR -...
LncRNA SNHG15 regulated autophagy and prevented cerebral ischaemia-reperfusion injury through mediating the miR-153-3p/ATG5 axis.doi:10.1111/jcmm.17956Yunhu YuYunpeng CaiHang ZhouJOURNAL of CELLULAR and MOLECULAR MEDICINE
Lnc RNA SNHG15通过靶向mi R-141/PD-L1促进胃癌的免疫逃逸为证明Lnc RNA SNHG15通过靶向另一种胃癌细胞系(MKN45)中的mi R-141/PDL1来促进胃癌的免疫逃逸.首先,我们检测了MKN45细胞中lnc RNA SNHG15和mi R-141的表达.与正常人胃上皮细胞(GES-1)相比,MKN45细胞中Lnc RNA SNHG15的表达明显升高,而mi ...
There are comments on PubPeer for publication: SNHG15 affects the growth of glioma microvascular endothelial cells by negatively regulating miR-153 (2017)
细胞株中发现长链非编码RNA-SNHG15它能抑制甲状腺癌细胞的增殖和诱导细胞凋亡,其他机制可能与caspase-3及Bax蛋白上调,Bcl-2蛋白下调表达有关[5].LncRNASNHG15定位于7号染色体(7p13 Chromosome)[6].在肝癌[6],胃癌[7]等它参与细胞增殖,凋亡,肿瘤发生和发展的调控过程.YANG DU研究表明长链非编码RNA SNHG15在...
Long noncoding RNA SNHG15 serves as an oncogene and predicts poor prognosis in epithelial ovarian cancer pubmed: 30588034 doi: 10.2147/ott.s182657 issn: 1178-6930 Elisabeth M Bikcomment accepted February 2021 July 2020 Expression of Concern, which reads:...
osteosarcomaSNHG15miR-346TRAF4Osteosarcoma (OS) is a common primary malignant bone tumor around the world. It has been reported that long noncoding RNAs (lncRNAs) take part in diverse pathological processes of OS; however, the mechanism remains unknown. This study aimed to uncover the profile ...
结果 LncRNA SNHG12,SNHG15及SNHG16在肺腺癌组织中的表达量均高于癌旁组织.但是这种表达差异与肺腺癌患者的性别,年龄,淋巴结转移及五年生存率等临床病理特征无相关性.仅SNHG15和SNHG16的表达与TNM分期有关.其表达越高,TNM分期越低.结论 SNHG15和SNHG16可能参与了肺腺癌的发生发展,并导致了患者的不良预后...
SNHG15 was observed in the ischemic hind limb of diabetic mice and high glucose (HG)-treated HUVECs. Functionally, the overexpression of SNHG15 promoted cell proliferation, migration, and tube formation, and suppressed cell apoptosis in HG-treated HUVECs. Mechanistically, SNHG15 reduced ...
LncRNA SNHG15 promotes the proliferation of nasopharyngeal carcinoma via sponging miR-141-3p to upregulate KLF9. LncRNA SNHG15 promotes the proliferation of nasopharyngeal carcinoma via sponging miR-141-3p to upregulate KLF9.Nasopharyngeal carcinomaSNHG15Proliferation,MiR... T Yi,X Lv,H Fan,.....