Small Vessel Ischemic DiseaseIschemic leukoaraiosis; Lacunar infarction; Periventricular white matter change; Selective incomplete white matter infarction; Subcortical vascular leukoencephalopathy; White matter disease Cerebral...doi:10.1007/978-3-319-56782-2_497-2Angela Eastvold...
CONCLUSIONS: Cerebral small vessel disease, with or without a history of cerebrovascular disease, is associated with increased risk of death and ischemic stroke in patients with atherosclerotic disease. 展开 关键词: Humans Cerebrovascular Disorders Brain Ischemia Magnetic Resonance Imaging Risk Factors ...
Cerebral small vessel disease (cSVD) is a collective term for different pathological processes that affect the small vessels of the brain, i.e. the small arteries and veins and the capillary beds. cSVD accounts for a quarter of ischemic strokes and is a main cause of vascular dementia (Debet...
Perturbations of the cerebrovascular matrisome: a convergent mechanism in small vessel disease of the brain? J Cereb Blood Flow Metab. 2016;36(1):143-157. doi:10.1038/jcbfm.2015.62 PubMedGoogle ScholarCrossref 6. Debette S, Strbian D, Wardlaw JM, et al; European ...
Circadian Rhythms Predict Small Vessel Ischemic Disease.The author comments on the article "Cerebral small vessel disease is related to disturbed 24-h activity rhythms: A population-based study," by L. A. Zuurbier and colleagues. Topics discussed include the importance of circadian rhythm for ...
Increased serum alpha2-macroglobulin levels might be involved in the pathophysiology of acute ischemic stroke. Furthermore, serum alpha2-macroglobulin levels, which were associated with high-grade white matter lesions, may reflect the chronic pathophysiological condition of cerebral small vessel disease. ...
Cerebral small vessel disease (SVD) is a common accompaniment of aging, which has several neuroimaging manifestations including white matter changes (WMC), cerebral microbleeds (CMBs) and cerebral microinfarcts (CMIs). The associations of these SVD imaging features (especially CMBs and CMIs) with cog...
Senescent endothelial cells (ECs) could impair the integrity of the blood vessel endothelium, leading to vascular aging and a series of diseases, such as atherosclerosis, diabetes. Preventing or mitigating EC senescence might serve as a promising therape
Rene´ IF de Coo6, Jan C den Hollander7, Renske Oegema1, Douglas B Gould4 and Grazia MS Mancini*,1 Familial porencephaly, leukoencephalopathy and small-vessel disease belong to the spectrum of disorders ascribed to dominant mutations in the gene encoding for type IV collagen alpha-1 (COL...
Conclusion Frontal lobe atrophy in ischemic stroke patients may be associated with small vessel disease. The association between WMLs and FLA was predominant over atrophy of the parietal and temporal lobes, which suggests that the frontal lobe may be vulnerable to subcortical ischemic changes.Yangkun ...