The single-stranded DNA of the lagging strand created by the action of the helicase is covered by tightly binding single-stranded DNA-binding proteins. In E. coli, this protein is a tetramer known as single-stranded-binding (SSB) protein, which the ssDNA winds itself around, while in T4 an...
网络单链结合蛋白 网络释义 1. 单链结合蛋白 9、单链结合蛋白(SSBP-single-strand binding protein):稳定已被解开的DNA单 链,阻止复性和保护单链不被核酸酶降解。 ( … wenku.baidu.com|基于7个网页
It must be inconsequential for the formation of RecA filaments in vitro, because other single-strand binding proteins can substitute for SSB in this function. Many studies indicate that the elimination of secondary structure in the ssDNA is the unique function of SSB in presynapsis. Once RecA ...
SSBP1 (Single-stranded DNA-binding Protein, Mitochondrial, Mt-SSB, MtSSB, PWP1-interacting Protein 17, SSBP) 供应商 MyBioSource 产品货号 MBS631975 产品报价 ￥询价/0.1mg ￥询价/5x0.1mg ￥询价/其它规格 产品说明书 点击查看 购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支...
As a result, A3A-induced mutations are enriched at hairpin-forming regions of cancer genomes and show strand bias for replication intermediates. It is also possible that larger ssDNA binding proteins, like RNA Polymerase occlude A3A binding. In our in vitro transcription assay, a 99 kDa T7 ...
3National Center for Protein Science Shang- hai, 320 Yueyang Road, Shanghai 200031, China Human single-strand (ss) DNA binding proteins 1 and 2 (hSSB1 and 2) are components of the hSSB1/2-INTS3- C9orf80 heterotrimeric protein complex shown to participate in DNA damage response and maint...
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Guidelines for expressing Cas proteins and sgRNA within the CRISPR/Cas system. In the CRISPR/Cas9 system (A), the Cas9-sgRNA complex initiates a double-strand break (DSB) close to a protospacer adjacent motif (PAM), typically “NGG” for Cas9 from S. pyogenes. To efficiently target the nuc...
Whether these proteins protect the reversed arm by physically blocking access to it or through other means has not been fully elucidated [53,54]. More recently, RAD51 has been found to specifically promote fork reversal by bypassing the CMG helicase using strand exchange activity [54]. This ...