SingleParticle.com is the premium provider of turn-key cryo-EM computing solutions, including GPU workstations and compute/storage clusters.
Understanding the complexity of cancer with cryo-EM Download eBook Scientific webinars Hear from the scientific community using single particle cryo-EM to empower their research. View gallery Electron Microscopy Funding Support Center Access technical content, Thermo Fisher Scientific Financial Ser...
Understanding the complexity of cancer with cryo-EM Download eBook Scientific webinars Hear from the scientific community using single particle cryo-EM to empower their research. View gallery Electron Microscopy Funding Support Center Access technical content, Thermo Fisher Scientific Financial Ser...
Understanding the complexity of cancer with cryo-EM Download eBook Scientific webinars Hear from the scientific community using single particle cryo-EM to empower their research. View gallery Electron Microscopy Funding Support Center Access technical content, Thermo Fisher Scientific Financial Services, and...
Since cytoskeletal polymers are difficult to crystallize, cryo-EM has been the predominant method of choice to study their structures. Recent advances in the methodology have enabled reconstructions at near-atomic resolution. In this review, we focus on novel insights gained from high-resolution cryo...
Electron cryo-microscopy (cryo-EM) single-particle analysis has yielded protein structures with increasing levels of detail in recent years1,2. However, it has proved difficult to obtain cryo-EM reconstructions with sufficient resolution to visualize individual atoms in proteins. Here we use a new ...
micrographs of rotavirus and HIV-1 virus-like particles were imaged using ptychography reporting the principal applicability to biological specimens albeit at low resolution27. Thus far, complete three-dimensional (3D) single-particle cryo-EM structures of biological macromolecules at close-to-atomic reso...
程亦凡《Structural Biology in the Era of Single-Particle CryoEM》是直播回放 | 结构+AI: 冷冻电镜与药物创新发现论坛的第2集视频,该合集共计14集,视频收藏或关注UP主,及时了解更多相关视频内容。
CryoEM Processing|CryoEM 数据处理-transfer cryoSPARC single particle to RELION 单颗粒冷冻电镜数据处理中用的比较多的软件是RELION和CryoSPARC。两者各有利弊,且不同的人有不同的使用倾向。笔者认为,RELION的MotionCorr和Polish较好,而CryoSPARC的2D,Nu-refinement则较优。对于有些比较难处理的数据集,有些人会将两...
In single-particle cryo-EM, the 3D molecular structure needs to be determined from many noisy 2D tomographic projections of individual molecules, whose orientations and positions are unknown. The high level of noise and the unknown pose parameters are two key elements that make reconstruction a ...