一种携带shSTAT3/shPD-L1重组质粒的减毒沙门氏菌载体及其应用本发明公开了一种携带shSTAT3/shPDL1重组质粒的减毒沙门氏菌载体及其应用,属于生物技术领域.本发明在同一个表达载体中采用两个启动子分别表达两个shRNA,成功构建携带shSTAT3/shPDL1重组质粒的减毒沙门氏菌载体;shSTAT3/shPDL1重组质粒能够同时沉默结...
一种携带shSTAT3/shPD-L1重组质粒的减毒沙门氏菌载体及其应用专利信息由爱企查专利频道提供,一种携带shSTAT3/shPD-L1重组质粒的减毒沙门氏菌载体及其应用说明:本发明公开了一种携带shSTAT3/shPD‑L1重组质粒的减毒沙门氏菌载体及其应用,属于生物技术领...专利查询请上
Moreover, RCAd-LTH-shPD-L1 exerted a specific cytotoxic effect on human cancer cells, but not on murine cancer cells or normal human cells. RCAd-LTH-shPD-L1 elicited a more potent antitumor effect in an immunodeficient mouse model and a humanized immune system mouse model than RCAd-shPD-L1...