Here, we report the cloning of the Pst resistance gene YrNAM in this region using the method of sequencing trait-associated mutations (STAM). YrNAM encodes a non-canonical resistance protein with a NAM domain and a ZnF-BED domain. We show that both domains are required for resistance. ...
Here, we report the cloning of the Pst resistance gene YrNAM in this region using the method of sequencing trait-associated mutations (STAM). YrNAM encodes a non-canonical resistance protein with a NAM domain and a ZnF-BED domain. We show that both domains are required for resistance. ...
Plant genotype alone appears to be insufficient to explain trait variations. This study integrates GWAS, MWAS and mGWAS in 827 foxtail millet cultivars, revealing that root-associated microbiota affect plant phenotypes in a host genotype-dependent manner. ...
Single nucleotide polymorphism (SNP), a common form of genetic variation, is caused by the transition, transversion, insertion, or deletion of individual bases. Expression quantitative trait loci (eQTL) analysis can profile genetic variations (especially SNP) that affect gene expression, offering enhan...
Whole Genome SequencingFamilial Mediterranean fever (FMF) is the most common auto﹊nflammatory disease. It is transmitted as autosomal recessive trait with mutations in MEditerranean FeVer (MEFV) gene. Despite a typical clinical expression, many patients have either a single or no mutation in MEFV....
Single nucleotide polymorphism (SNP), a common form of genetic variation, is caused by the transition, transversion, insertion, or deletion of individual bases. Expression quantitative trait loci (eQTL) analysis can profile genetic variations (especially SNP) that affect gene expression, offering enhan...
Reverse hybridization analysis for the most common globin mutations identified IVSII1 (GA) in the heterozygous state. The maternal laboratory data indicated ... B Moghimi,M Yavarian,C Oberkanins,... - 《Hemoglobin》 被引量: 10发表: 2004年 Abnormal hemoglobins associated with the beta-globin ...
Once a hit that alters the phenotypic trait of interest is uncovered, the next step is to gain insights into the underlying biologic processes. Post-ENU Screening Individual mutations identified from anENUmutagenesisscreen need to be first mapped to a chromosomal location. Such mapping is conducted...
(SNP) GWAS variants lie outside of genes and/or are not in linkage disequilibrium with polymorphisms affecting amino-acid sequence,9,10and functional consequences of candidate variants remain largely unclear. Disease-associated copy-number variants (CNVs) and trait-associated SNPs from GWAS on ...
In mice and rats, increased tameness is considered the critical trait of domestication [2, 5]. Modification in behavior, especially increased tameness, occurs in nearly all domestic animals [1, 6]. Loci associated with the nervous system and/or behavior are observed in dogs and cats [7, 8]...