Here, we report the cloning of the Pst resistance gene YrNAM in this region using the method of sequencing trait-associated mutations (STAM). YrNAM encodes a non-canonical resistance protein with a NAM domain and a ZnF-BED domain. We show that both domains are required for resistance. ...
Article https://doi.org/10.1038/s41467-023-39993-2 Sequencing trait-associated mutations to clone wheat rust-resistance gene YrNAM Received: 25 October 2022 Accepted: 6 July 2023 Check for updates Fei Ni 1, Yanyan Zheng1,5, Xiaoke Liu1, Yang Yu 1, Guangqiang Zhang1,2, Lynn Epstein 3,...
Plant genotype alone appears to be insufficient to explain trait variations. This study integrates GWAS, MWAS and mGWAS in 827 foxtail millet cultivars, revealing that root-associated microbiota affect plant phenotypes in a host genotype-dependent manner. ...
Whole Genome SequencingFamilial Mediterranean fever (FMF) is the most common auto﹊nflammatory disease. It is transmitted as autosomal recessive trait with mutations in MEditerranean FeVer (MEFV) gene. Despite a typical clinical expression, many patients have either a single or no mutation in MEFV....
Single nucleotide polymorphism (SNP), a common form of genetic variation, is caused by the transition, transversion, insertion, or deletion of individual bases. Expression quantitative trait loci (eQTL) analysis can profile genetic variations (especially SNP) that affect gene expression, offering enhan...
Single nucleotide polymorphism (SNP), a common form of genetic variation, is caused by the transition, transversion, insertion, or deletion of individual bases. Expression quantitative trait loci (eQTL) analysis can profile genetic variations (especially SNP) that affect gene expression, offering enhan...
Step-wise increase in tigecycline resistance in Klebsiella pneumoniae associated with mutations in ramR, lon and rpsJ. PLoS One. 2016;11:e0165019. 27. Liu YY, Wang Y, Walsh TR, Yi LX, Zhang R, Spencer J, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in ...
Traditionally, knowledge of a phenotype that varies between populations is required to accurately prove that a polymorphism is associated with a specific adaptation or trait. However, using a reverse ecology population genomic approach, two cryptic populations of the fungus Neurospora crassa were ...
In the present study, we analyzed RGAs in the sugar beet genome to identify polymorphic sequences that differentiate wild accessions from domesticated beets. Although domestication is associated with the loss of resistance to biotic and abiotic stresses, it can be regarded as the selection of suitab...
This is especially the case when trying to improve elite materials for a certain trait or a few traits since the presence of numerous undesirable mutations in the background may disrupt the finely tuned genetic architecture of the elite variety. In the present study, there were only nine ...