Vaccine development targeting rapidly evolving pathogens such as HIV-1 requires induction of broadly neutralizing antibodies (bnAbs) with conserved paratopes and mutations, and in some cases, the same Ig-heavy chains. The current trial-and-error search for immunogen modifications that improve selection...
GO terms enrichment analysis revealed a significant enrichment of various biological functions within genes over-transcribed in the Transflu-R line (Additional file 4A). Many enriched functions were related to P450 activity, including 'oxidoreductase activity', 'monooxygenase activity', 'heme binding' ...
Answer to: Along with proteins, ___ forms the structure of the ribosome. Select all that apply. a. Messenger RNA b. Transfer RNA c. Ribosomal...
There are four categories of macromolecules: carbohydrates, nucleic acids, proteins, and lipids. Macromolecules are essentially the "building blocks" of cells. Each of these macromolecules, which are types of polymers, are built by combining a series of smaller molecules k...
The researchers tested their new sensor in two types of human cancer cells: one set that they knew was susceptible to a redox drug, and another that they knew was not susceptible. The sensor revealed that hydrogen peroxide levels were unchanged in the resistant cells but went up in the susce...
28, 33, 34 However the observations that in the skin, inhibition of either E-selectin or P-selectin alone dramatically reduces leukocyte recruitment raises the possibility that these two molecules are playing critical, yet nonoverlapping functions. Given that the types of leukocytes recruited by each...
What is a polysaccharide? Learn the definition of a polysaccharide, its structures, functions, characteristics, and the various types. See examples of some polysaccharide molecules with their typical structure. Related to this Questio...
The selectins are a family of integral membrane proteins characterized by the presence of lectin-, epidermal growth fac- tor, and complement-binding domains (25, 26). L-selectin was previously known as LEC.CAM-1, LECAM-I, LAM I, and as the MEL-14, Leu-8, TQ1, and Dreg-56 antigen...
The apparent dominance of loline-catabo- most of the XRE family regulators are hypothetical lizing strains in the phyllosphere community of proteins, and thus no prediction can be made of loline-containing plants indicates that they are general functions for most members of this protein being ...
Cancer cells are known to secrete K8-containing protein complexes in vitro and in vivo. These complexes bind plasminogen as well. The plasminogen-binding activity of K8 is unique amongst IF proteins, probably because its sequence includes a carboxyl-terminal Lys residue. However, a K8 mutant that...