SB431542,TGF-betaInhibitor 的详细介绍 Product Information Molecular Weight: 384.39 Formula: C22H16N4O3 Purity: ≥98% CAS#: 301836-41-9 Solubility: DMSO up to 100mM Chemical Name: 4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide Storage: Powder: 4oC 1...
SB505124是一种选择性TGFβR抑制剂,作用于ALK4和ALK5,无细胞试验中IC50分别为129 nM和47 nM,也抑制ALK7,但不抑制ALK1,2,3或6。An inhibitor of Activin receptor-like kinase 5 SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays,...
TGFβ inhibitionSTUDY QUESTION Is there an effect of the TGFβ inhibitor SB431542 (SB) on the epiblast compartment of human blastocysts, and does it affect subsequent human embryonic stem cell (hESC) derivation? SUMMARY ANSWER SB increases the mean number of NANOG-positive cells in the inner ...
SB-505124是一种选择性的TGFβR抑制剂,对ALK4,ALK5的IC50值分别为129nM和47nM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:694433-59-5纯度:99.73%分子式:C20H21N3O2分子量:335.4结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:TGFβR抑制剂(SB-...
View and buy high quality SB 525334. Selective inhibitor of TGF-βRI. Cited in 7 publications.
产品活性:SB-505124 是一种选择性的 TGF-βI 型受体 (ALK4,ALK5,ALK7) 抑制剂,对 ALK4,ALK5 的 IC50 值分别为 129 nM 和 47 nM,对 ALK1,2,3 或 6 无作用。 生物活性:SB-505124 是一种选择性抑制剂?TGF-β Receptor type I receptors(ALK4,ALK5,ALK7), 对 ALK4、ALK5 的IC50s 分别为 ...
TGF-beta/Smad ¥ 233 现货 规格 数量 客户已引用 A 83-01 ALK5 Inhibitor IV, A8301 T3031909910-43-6 A 83-01 (ALK5 Inhibitor IV) 是一种 TGF-βI 型受体 ALK5、ALK4 和 ALK7 的抑制剂 (IC50=12/45/7.5 nM)。A 83-01 可促进小鼠成纤维细胞重编程为 iPSCs。A 83-01 可用于类器官培养...
Previous animal studies have indicated that Transforming Growth Factor-β (TGF-β) signaling may play an important role in the development of these muscle pathologies after injury. Here, we demonstrated that inhibition of TGF-β1 signaling with the small molecule inhibitor SB431542 in a mouse ...
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells. ...
An effective and selective inhibitor of ALK5 (IC50: 94 nM in a cell-free assay). ●SB525334(CAS:356559-20-1) A potent and selective inhibitor of TGFβ receptor I (ALK5). ●LY2109761(CAS:700874-71-1) A TβRI/II dual inhibitor( Ki: 38...