Role of TGF beta in the anti-estrogen response/resistance of human breast cancer. J Mammary Gland Biol Neoplasia. 1996; 1 :381–389.Benson JR, Baum M, Colletta AA (1996) Role of TGF beta in the anti-estrogen response/resistance of human breast cancer. J Mammary Gland Biol Neoplasia 1:...
lymphatics and nerves, making its repair a big challenge. Transforming growth factor-beta 3 (TGF-β3), a vital member of the highly conserved TGF-β superfamily, plays a versatile role in cartilage physiology and pathology. TGF-β3 influences the whole life cycle of chondrocytes...
Role of TGFbeta in stem cells and cancer. Oncogene 2005; 24:5667.Roberts A, Mishra L: Role of TGF-beta in stem cells and cancer. Oncogene 24(37):5667, 2005Roberts A, Mishra L. Role of TGF-β in stem cells and cancer. Oncogene. 2005; 24 :5667....
Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003; 113:685–700. Article PubMed CAS Google Scholar Derynck R, Feng XH. TGF-beta receptor signaling. Biochim Biophys Acta 1997; 1333:F105–F150. PubMed CAS Google Scholar Itoh S, Itoh F, Goumans MJ, ten ...
In most of these biological processes, which resemble metastasis, transforming growth factor-beta (TGF-βs) and their high-affinity receptors are involved directly or indirectly. TGF-βs are abundantly and differentially expressed in the endometrium under hormonal control. Although they are ...
CONCLUSION: TGF-β has a dual role in tumorigenesis; it acts as a tumor suppressor in early stage but promotes tumor cell invasion and metastasis in advanced stage. High level of TGF-β was found only in liver cancer patients with metastasis. 展开 关键词: Hepatocellular carcinoma Transforming ...
Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-beta1 blocker. Muscle Nerve. 2011;43(1):82–7. doi:10.1002/mus.21869. Article CAS PubMed Google Scholar Download references Acknowledgements This work was supported by NIH grant U01CA143057, the Susan G. Komen ...
Evidence that transforming growth factor beta (TGF-β)4 influences pattern formation in the developing mammary gland and negatively regulates ductal growth is reviewed. In the mouse, overexpression of TGF-β transgenes during puberty reduces the rate of growth of the ductal tree and simplifies the ...
A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells. Oncogene 2002;21:7147-55.Lauritsen K J,List H J,Reiter R,et al.A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor...
Transforming growth factor beta (TGF beta) has potent inhibitory effects upon epithelial proliferation and malignant progression may be associated with breakdown of the autocrine and paracrine inhibitory loops in which TGF beta participates. The therapeutic effecs of anti-estrogens may be partially attribu...