文章标题:A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma. 01研究背景 肢端黑色素瘤(AM)是一种发生在肢端皮肤的黑色素瘤(CM)亚型,最近的研究显示,免疫疗法对黑色素瘤的治疗响应率可达到38%,但对AM的响应率只有16.6%。该研究旨在通过单细胞测序,从肿瘤异质性和免疫环...
RNA-seq analysis reveals the potential mechanism of improved viability and product quality of tea plants through intercropping with Chinese chestnutCamellia sinensisIntercroppingRNA-seqTranscription factorsQuality of green teaTea is one of the top industrial crops in China and being consumed all over the...
www.nature.com/scientificreports OPEN RNA‑seq analysis reveals the genes/pathways responsible for genetic plasticity of rice to varying environmental conditions on direct‑sowing and transplanting Suresh Kumar 1*, Karishma Seem1, Santosh Kumar2 & Trilochan Mohapatra3 ...
RNA-seq analysis reveals extensive transcriptional plasticity to temperature stress in a freshwater fish species. BMC Genomics 14, 375 (2013). https://doi.org/10.1186/1471-2164-14-375 Download citation Received29 January 2013 Accepted27 May 2013 Published05 June 2013 DOIhttps://doi.org/10.1186/...
[17]Zheng Q,Bao C,et al,Circular RNA profiling reveals an abundant circHIPK3 that regulated cell growth by sponging mutiple miRNAs. Nat Commun. 2016 Apr 6;7:11215 [18] Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome...
RNA-seq analysis reveals different drought tolerance mechanisms in two broadly adapted wheat cultivars ‘TAM 111’ and ‘TAM 112’ Chenggen Chu, Shichen Wang, Li Paetzold, Zhen Wang, Kele Hui, Jackie C. Rudd, Qingwu Xue, Amir M. H. Ibrahim, Richard Metz, Charles D. Johnson...
RNA-Seq+qPCR，无参转录组揭示幼体硬壳蛤色素沉着分子机制 期刊：Genomics 影响因子：6.2 文章题目：De novo assembly transcriptome analysis reveals the preliminary molecularmechanism of pigmentation in juveniles of the hard clam Mercenaria mercenaria 发表期刊：Genomics 技术手段：RNA-Seq+qPCR 派森诺生物与中国...
ChIP–seq analysis 比对:GRCm38/mm10,Subread aligner peaks识别:Homer (v.4.9),FDR cutoff of 10-4 注释:Peaks were assigned to their nearest gene ATAC-seq和ChIP–seq联合:Overlapping peaks at least 1 bp overlap 主要结果 1 Sex-specific VAT T~reg~ cell molecular profile(RNA-seq结果) visceral ...
单细胞RNA测序(scRNA-seq)能够系统地识别组织中的细胞群,但表征它们的空间组织仍然具有挑战性。本研究结合了基于微阵列的空间转录组(ST)方法,利用一系列spots揭示基因表达的空间模式。开发了Multimodal intersection analysis (MIA)多模式交叉分析,对原发性胰腺肿瘤应用发现导管细胞、巨噬细胞、树突状细胞和癌细胞的亚群...
单细胞RNA测序(scRNA-seq)能够系统地识别组织中的细胞群,但表征它们的空间组织仍然具有挑战性。本研究结合了基于微阵列的空间转录组(ST)方法,利用一系列spots揭示基因表达的空间模式。开发了Multimodal intersection analysis (MIA)多模式交叉分析,对原发性胰腺肿瘤应用发现导管细胞、巨噬细胞、树突状细胞和癌细胞的亚群...