RNA-DNA interactions can serve as a signal that triggers de novo DNA methylation in plants. As yet, this RNA-directed DNA methylation mechanism merely targets transgenes, but it appears likely that methylation of some endogenous sequences is also directed by RNA. RNA-directed methylation of ...
Non-Coding RNA Transcription and RNA-Directed DNA Methylation in Arabidopsis Two atypical DNA-dependent RNA polymerases, Pol IV and Pol V, play critical roles in RNA-directed DNA methylation. We summarize the mechanisms for Pol IV a... XJ He,ZY Ma,ZW Liu - 《分子植物(英文版)》 被引量:...
RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic pathway in plants. RdDM requires a specialized transcriptional machinery that comprises two plant-specific RNA polymerases - Pol IV and Pol V - and a growing number of accessory proteins, the functions of which in the...
A sequence-specific silencing of DNA. The methylation may be limited to as short as 30-base sequences but it extends generally to longer stretches (Pélissier T, Wassenegger M 2000 RNA 6:55). Argonaute 4 plays both catalytic and non-catalytic roles in DNA methylation through the RNAi ...
et al. RNA silencing genes control de novo DNA methylation. Science 303, 1336 (2004). Article CAS PubMed Google Scholar Haag, J. R. & Pikaard, C. S. Multisubunit RNA polymerases IV and V: purveyors of non-coding RNA for plant gene silencing. Nature Rev. Mol. Cell Biol. 12, 483...
www.nature.com/scientificreports OPEN Genome-wide identification of endogenous RNA-directed DNA methylation loci associated with received: 03 August 2016 accepted: 12 October 2016 Published: 27 October 2016 abundant 21-nucleotide siRNAs in Arabidopsis Jian-Hua Zhao1,Yuan-Yuan Fang1, Cheng-Guo...
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DRD1 (defective in RNA-directed DNA methylation) is a putative SWI2/SNF2-like chromatin remodelling protein; DRD2 and DRD3 (renamed NRPD2a and NRPD1b, respectively) are subunits of Pol IVb, a putative RNA polymerase found only in plants. Interestingly, DRD1 and Pol IVb appear to be ...
DNA 甲基化 1. Purpose:To verify the effect of folate deficiency on fetal rats intrauterine brain development,the change of DNA methylation in fetal rats brain with maternal folate deficiency was studied. 目的:探讨叶酸缺乏对胎鼠宫内脑发育的影响,研究叶酸缺乏孕鼠子代脑组织基因组 DNA 甲基化水平的...
Yin, Q. Zhuge, RNA-directed DNA methylation in plants, Plant Cell Rep. 34 (2015) 1857-1862.Movahedi A, Sun W B, Zhang J X, Wu X L, Mousavi M, Mohammadi K, Yin T M, Zhuge Q. RNA-directed DNA methylation in plants. Plant Cell Reports, 2015, DOI 10.1007/s00299-015-1839-0....