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11. The roles of small RNAs in the regulation of agronomic traits of crops(Written by Yijun Qi) 12. Open questions in the study of RNA-directed DNA methylation(Written by Craig S. Pikaard) Figure 10. Establishment and maintenance of DNA methylation by RdDM. 原文链接: https://academic.oup....
Transcriptional gene silencing via RNA-directed DNA methylation (RdDM) guides the epigenetic regulation of the genome in response to disease states, growth, developmental and stress signals. RdDM machinery is composed of proteins that produce and modify 24-nt- long siRNAs, recruit the RdDM complex ...
DNA methylation at a gene promoter can be triggered by double-stranded RNAs (dsRNAs) through the RNA-directed DNA methylation (RdDM) pathway and induces tr... S Otagaki,M Kawai,C Masuta,... - 《Epigenetics》 被引量: 63发表: 2011年 A subgroup of SGS3-like proteins act redundantly in ...
Methylation of a previously unmodified DNA sequence. Small interfering RNAs (siRNAs) in the RNA-directed DNA methylation pathway are well-known triggers of sequence-specific de novo methylation of cytosines in all sequence contexts. Silencing effector complex A multiprotein complex that elicits RNA in...
RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic pathway in plants. RdDM requires a specialized transcriptional machinery that comprises two plant-specific RNA polymerases - Pol IV and Pol V - and a growing number of accessory proteins, the functions of which in the...
12. Yang,D.L., Zhang,G., Tang,K., Li,J., Yang,L., Huang,H., Zhang,H. and Zhu,J.K. (2016) Dicer-independent RNA-directed DNA methylation in Arabidopsis. Cell Res., 26, 66–82. 13. Ye,R., Chen,Z., Lian,B., Rowley,M.J., Xia,N., Chai,J., Li,Y., He,X.J., ...
Transcriptional silencing via RNA-directed DNA methylation and chromatin modification involves two forms of nuclear RNA polymerase IV (Pol IVa and Pol IVb), RNA-dependent RNA polymerase2 (RDR2), DICER-LIKE3 (DCL3), ARGONAUTE4 (AGO4), the chromatin remodeler, DRD1, and the de novo cytosine...
1、RNARNA介导的介导的DNADNA甲基化甲基化RNA-directed DNA methylation: an epigenetic pathway of increasing complexity王 明强2015717011江苏省中国科学院植物研究所表观遗传表观遗传同卵双生:奥利维亚和伊莎贝拉同卵双生:奥利维亚和伊莎贝拉在基因的在基因的DNA序列不序列不发生改变的情况下,发生改变的情况下,基因表达...