【1】Protein synthesis is anelaborateprocess starting from the nucleus and ending in the cytoplasm. 蛋白质合成是一个从在细胞核中开始到在细胞质中结束的复杂过程。【elaborate 精心制作的】 【2】Protein synthesis is referred t...
protein turnovernucleoid structurechaperonesCovers the myriad features of DNA, RNA, and protein synthesis. The topics discussed include the bacterial nucleoid, ribosomes, DNA synthesis, transcription, translation, processing of RNA transcripts, protein folding, chaperones, protein secretion, and protein ...
近日,英国剑桥MRC分子生物学实验室(MRC-LMB)的Venki Ramakrishnan(2009年诺贝尔化学奖得主)团队在Nature Biomedical Engineering发表了一篇题为Efficient circular RNA synthesis for potent rolling circle translation的文章(杜易飞博士为第一作者兼共同通讯作者),介...
近日,英国剑桥MRC分子生物学实验室 (MRC-LMB) 的Venki Ramakrishnan (2009年诺贝尔化学奖得主) 团队在Nature Biomedical Engineering发表了一篇题为Efficient circular RNA synthesis for potent rolling circle translation的文章 (杜易飞博士为第一作者兼共同通讯作者) ,介绍了一种高效且精准的环状RNA合成技术,并将高效的...
et al. Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR. Nat Biotechnol 41, 698–707 (2023). https://doi.org/10.1038/s41587-022-01534-5 Download citation Received23 May 2022 Accepted28 September 2022 Published27 October 2022 Issue DateMay 2023 DOIhttps://doi.org/...
Austria Advances in next-generation sequencing and mass spec- m6A methylation and adenosine to inosine editing (A-to-I edit- trometry have revealed widespread messenger RNA ing). For other epitranscriptomic mechanisms such as cytosine modifications and RNA editing, with dramatic effects on to uracil...
Ribosome-bound mRNA mapping (RIBOmap) enables three-dimensional in situ detection of spatially resolved protein synthesis in single cells. Lei Tang Article|07 August 2023 Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender ...
A prominent example of an RNA-binding protein with multiple roles is SF2/ASF, which was originally identified as an essential splicing factor, and has now been implicated in translational control [77] and miRNA processing [78]. Second, a number of RNA-binding proteins, including the Arabidopsis...
(Fig.6). RNA editing, as a co/posttranscriptional modification, can change nucleotide sequences and have important effects on viral replication, protein synthesis, infection, and virulence. ADARs and APOBECs, in addition to deamination, are RNA-binding proteins that directly interact with endogenous...
After allowing 30 min for protein synthesis, the labeled products were electrophoresed and measured the radioactivity. Several lines of evidence indicate that poly(A) also enhances the translatability of an mRNA. Poly(A) enhances both the lifetime and translatability of mRNA. At least in rabbit ...