Arsenic resistance protein 2 (ARS2), a nuclear protein encoded by the human SRRT gene (Serrate RNA effector molecule homolog)103, was initially identified as the gene that confers arsenite resistance on mammalian cells104. Functional studies have shown that ARS2 is highly expressed in proliferating...
这期推荐在线基因功能富集分析(g:Profiler –a web server for functional enrichment analysis and conversions of gene lists),下面我们就看看怎么来实现吧! 简介 g:Profiler是一个可靠的和最新的功能富集分析工具,支持各种证据类型,标识符类型和生物体。该工具集集成了包括Gene Ontology、KEGG和TRANSFAC在内的多个数据...
proteins implicated in regulation of alternative splicing, and protein components of snRNPs. In vitro studies showed that the rat homolog bound to RNA homopolymers, with a preference for G and U polyribonucleotides. This gene is part of a gene cluster on chromosome Xp11.23, and its 3' end ...
产品名称: 冷诱导 RNA 结合蛋白 (CIRBP) 重组蛋白 英文名称:Recombinant Cold Inducible RNA Binding Protein (CIRBP) 英文别名:CIRP; A18HNRNP; Glycine-Rich RNA Binding Protein 来源:原核表达 物种: ( 人、大鼠
RNA-Binding proteins Gene pairs Signature Gastric cancer The cancer genome atlas Gene expression omnibus 1. Introduction Gastric cancer (GC) is the third cancer-related cause of death in the world and one of the most common malignant tumors [1]. In recent years, despite the continuous improvemen...
A gene ontology (GO) analysis also shows that eRIC hits are associated with terms mainly related to RNA metabolism, including translation, ribonucleoprotein complex, or mRNA binding (Fig. 2b and Supplementary Data 8). Moreover, most eRIC hits belong to the RNA-related protein groups “nucleic ...
MicroRNA (miRNA) biogenesis is finely controlled by complex layers of post-transcriptional regulators, including RNA-binding proteins (RBPs). Here, we show that an RBP, QKI5, activates the processing of primary miR-124-1 (pri-124-1) during erythropoiesis
The ligand-binding event induces conformational changes in the riboswitch that are then transmitted to the gene expression apparatus. Probing the mechanisms of such a fine regulation at atomic resolution is very difficult experimentally and molecular dynamics (MD) could be used to quantify the ligand-...
Entrez Gene ID:(Human) 5430 功能 RNA polymerase II activityDNA bindingDNA-directed RNA polymerase activityRNA-directed RNA polymerase activityprotein bindingubiquitin protein ligase bindingpoly(A) RNA bindingmetal ion bindingDNA-directed RNA polymerase ...
The single sample gene set enrichment analysis (ssGSEA) algorithm was used to quantify the relative abundance of each cell infiltration in the TME of BC patients [22]. We obtained the signature gene sets indicating a wide range of human immune cell subtypes from Charoentong’s research, includi...