Barcellos-Hoff MH, Kleinberg DL. 2013. Breast cancer risk in BRCA1 mutation carriers: Insight from mouse models. Ann Oncol 24:viii8-viii12.M. H. Barcellos-Hoff , D. L. Kleinberg . (2013) Breast cancer risk in BRCA1 mutation carriers: insight from mouse models. Annals of Oncology 24 ...
- 《Journal of the National Cancer Institute》 被引量: 890发表: 2002年 Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients Background Ten patients with breast cancer and a breast cancer susceptibility gene 1 (BRCA1) mutation, who presented with stages I to ...
To estimate the risk for contralateral breast cancer in members of BRCA1- and BRCA2-positive families and to determine predictive risk factors. A retrospective, multicenter, cohort study was performed from 1996 until 2008 and comprised 2,020 women with unilateral breast cancer (index patients, n ...
Jolie has a genetic mutation to one of her BRCA genes—specifically the BRCA1 gene. We all have BRCA genes, which function as tumor suppressors. These genes are essential for healthy cell survival andcancer prevention. They act to repair our DNA and fix errors that occur due to aging or e...
J. et al. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet. 9, e1003212 (2013). 6. Birney, E. & Soranzo, N. Human genomics: The end of the start for population sequencing. Nature 526, 52–53 (...
but their impact for BRCA-mutation carriers with a history of early-onset breast cancer is less clear," said presenter Matteo Lambertini, MD, Ph.D., an associate professor ofmedical oncologyand consultant in medical oncology at the University of Genova-IRCCS Policlinico San Martino Hospital in Ge...
(2017). Longitudinal cancer risk management trajectories of BRCA1/2 mutation-positive reproductive-age women. Journal of Psychosocial Oncology. Ahead of Print. doi: 10.1080/07347332.2017.1292574doi:10.1080/07347332.2017.1292574Young, Jennifer Louise
et al. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum. Mol. Genet. 18, 4442–4456 (2009). Article CAS Google Scholar Lakhani, S.R. et al. The pathology of familial breast cancer: predictive value of immunohistochemical ...
et al. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nat. Genet. 42, 885–892 (2010). Article CAS PubMed PubMed Central Google Scholar Fletcher, O. et al. Novel ...
SummaryBackground: Women with a mutation in BRCA1 or BRCA2 have a high risk of developing breast cancer and of contralateral cancer after the initial diagn... Narod,A Steven,Brunet,... - 《Lancet》 被引量: 571发表: 2000年 Tamoxifen and contralateral breast cancer inBRCA1 andBRCA2 carriers...