TNF Superfamily Pathway: Human Ligand-Receptor Interactions & their Associated Functions Toll-Like Receptor Signaling Pathways Type I Interferon Signaling Pathways Type II Interferon Signaling Pathways Type III Interferon Signaling Pathways VEGF - VEGF R2 Signaling Pathways ...
Wang and colleagues show that in skeletal muscle cells and cardiomyocytes, the glucose transporter GLUT4 is a negative regulator of RIG-I-like receptor signaling during viral infection by redistributing RIG-I and MDA5 to the plasma membrane and attenuating interferon responses. Andrew G. Harrison ...
RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway. Protein & cell. 2017;8:165-8.Chattopadhyay, S., & Sen, G. C. (2017). RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway. Protein and Cell, 8...
RIG-I-Like Receptor Ligands RLRs are a family of DExD/H boxRNA helicasesthat recognize viral ds or uncapped RNAs within the cytosol of infected cells. They can initiate and modulateantiviral immunity[35]. To date, three RLR members have been identified: RIG-I (retinoic acid-inducible gene ...
RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection. Nat. Commun. 9, 4841 (2018). This manuscript reports the activation of RIG-I in KSHV-infected cells due to virus-induced defects in the normal post-transcriptional processing of cellular ...
在天然免疫反应中,宿主细胞的特异性受体能够识别病原相关分子模式(pathogen associated molecular patterns,PAMPs),从而诱导I型干扰素(IFNs)和炎性细胞因子产生。宿主细胞特异性受体被称为模式识别受体(pattern recognition receptors,PRRs),主要包括...
TOLL-LIKE RECEPTOR-3E3 UBIQUITINLIGASEDOUBLE-STRANDED-RNAIFN-BETA PROMOTERINDUCIBLE GENE-IThe RIG-I-like receptors (RLRs) RIG-I, MDA5, and LGP2 trigger innate immune responses against viral infections that serve to limit virus replication and to stimulate adaptive immunity. RLRs are cytosolic ...
Initiation of Hepatitis C Virus Infection Is Dependent on Cholesterol and Cooperativity between CD81 and Scavenger Receptor B Type I 热度: Clinical characteristics and outcome of respiratory syncytial virus infection among adults hospitalized with influenza-like illness in France ...
英文名称:Human Retinoic Acid Inducible Gene/RIG-1-like Receptor (RLR) ELISA Kit 产品规格:96T/48T 使用目的:本试剂盒用于测定人血清、血浆及相关液体样本中RLR含量。 运输方式:快递发货 保存条件及有效期 1.试剂盒保存:2-8℃。 2.有效期:6个月 特异性:本ELISA检测试剂盒可同时检测天然或重组的,...
The RIG-I like receptor pathway is stimulated during RNA virus infection by interaction between cytosolic RIG-I and viral RNA structures that contain short... ML Goulet,D Olagnier,Z Xu,... - 《Plos Pathogens》 被引量: 104发表: 2013年 FLN29 deficiency reveals its negative regulatory role in...