别名GAP1 like protein; MRASAL; RAS GTPase activating protein like; RAS protein activator like 1 (GAP1 like); RAS protein activator like 1; RASAL; Rasal1; rasGAP activating like protein 1; RasGAP-activating-like protein 1; RASGAP1 LIKE; RASL1_HUMAN. ...
Reduced expression of RAS protein activator like-1 in gastric cancer. Int J Cancer. 2011;128:1293–302.Seto M, Ohta M, Ikenoue T, Sugimoto T, Asaoka Y, Tada M, Mohri D, Kudo Y, Ijichi H, Tateishi K, et al: Reduced expression of RAS protein activator ...
CALDAG-GEFI; CALDAG-GEFII; Guanine nucleotide exchange factor, calcium and DAG regulated, Rap1A; hRasGRP1; Ras activator RasGRP; RAS guanyl nucleotide releasing protein 1; RAS guanyl releasing protein 1 (calcium and DAG-regulated); RAS guanyl releasing protein 1; RASGRP; RASGRP1; GRP1_HUMAN....
ML-098 is an activator of the GTP-binding protein Rab7 (EC50 = 77.6 nM). Quick View A16049 XRP44X Ras-Net inhibitor XRP44X is a Ras-Net (Elk-3) pathway inhibitor (IC50 = 10-20 nM). Indirectly inhibits Net phosphorylation upstream of Erk1/2 activation. ...
RASAL1 RAS protein-like activator 1 antibody information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
人STAT3蛋白抑制分子(PIAS3)ELISA试剂盒 Human Protein inhibitor of activated STAT3,PIAS3 ELISA kit 30-0295G-FITC FITC标记的羊抗兔IgG Goat Anti-rabbit IgG/FITC JW-E10634 Mouse Angiotensin converting enzyme,ACE ELISA试剂盒小鼠血管紧张素转化酶(ACE)ELISA试剂盒 96T/48T 国产/进口 人胎盘生长因子(PLGF...
Salirasib是一种有效的竞争性prenylated protein methyltransferase (PPMTase)抑制剂, Ki为2.6 μM,其抑制Ras甲基化。Phase 2。 Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2. 产品属性 关联靶点(人) ...
ARAF, BRAF, and CRAF comprise the RAF kinase family, all of which share a common upstream activator, RAS [169]. ZM336372 was the first small-molecule, ATP-competitive RAF inhibitor developed, targeting CRAF in cancer [170], However, among the first-generation RAF inhibitors, only Sorafenib ...
We describe the design, kinetic properties, and structures of engineered subtilisin proteases that degrade the active form of RAS by cleaving a conserved sequence in switch 2. RAS is a signaling protein that, when mutated, drives a third of human cancers
C. et al. Stabilizing a weak binding state for effectors in the human RAS protein by cyclen complexes. Angew. Chem. Int. Ed Engl. 49, 3830–3833 (2010). Article CAS PubMed Google Scholar Patgiri, A., Yadav, K. K., Arora, P. S. & Bar-Sagi, D. An orthosteric inhibitor of ...