Ras protein activator like 2 (RASAL2) has a cancer-related function, but plays inconsistent roles in different malignancies. This project was designed to determine the role of RASAL2 in carcinogenesis in gastric cancer. The Cancer Genome Atlas data revealed high levels of RASAL2 in gastric ...
To distinguish between inhibition of Ras by Ras GTPase-activating protein (GAP) versus a potential effector function of GAP, we tested the effector domain substitution P34R: this mutation, which abolishes GAP binding, enhanced Ras-dependent transcription in Mv1Lu cells, yet interfered with Ras-...
别名GAP1 like protein; MRASAL; RAS GTPase activating protein like; RAS protein activator like 1 (GAP1 like); RAS protein activator like 1; RASAL; Rasal1; rasGAP activating like protein 1; RasGAP-activating-like protein 1; RASGAP1 LIKE; RASL1_HUMAN. ...
产品规格: 50μl|100μl|150μl 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 抗体名称Anti-RASGAP/RASA1 Antibody 指标别名CM AVM;CMAVM;GAP;GTPase activating protein;p120GAP;p120RASGAP;PKWS;Ras p21 protein activator;RASA;RASA1;RASGAP ...
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 背景资料RASA1,also known as RAS p21 protein activator 1,is a 120-kDacytosolic human protein.The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating p...
英文名称: Rat RAS protein activator like 1(RASAL1)ELISA Kit 用途: 科研实验 产地: 上海 品牌: 科博瑞 包装规格: 96T/48T 标记物: HRP标记物 样本: 血清,血浆,唾液,尿液,组织,细胞上清,裂解液等 检测方法: 酶联免疫法 应用: 详见说明书 检测限: 详见说明书 货号: KBR-hlk5244 是否进...
别 名;GAP1M; GTPase activating protein of RAS; Ras GTPase activating protein 2; Ras GTPase-activating protein 2; RAS p21 protein activator 2; RASA2; RASA2_HUMAN; RASGAP. 第一抗体就是平常所说的抗体,即能和抗原特异性结合。 第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。 一...
Rozakis-Adcock, M., Fernley, R., Wade, J., Pawson, T. & Bowtell, D. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.Nature363, 83–85 (1993). CASPubMedGoogle Scholar Egan, S. E. et al. Association of Sos Ras exchange protein wi...
Ras interacts with Raf-1 and stimulates its kinase activity, which results in activation of the mitogen-activated protein (MAP) kinase cascade. It has been proposed that the main function of Ras in Raf-1 activation is to recruit Raf-1 to the plasma membrane, where a separate activation ...
RASAL, like Ca2+ -promoted Ras inactivator (CAPRI, or RASAL4), is a cytosolic protein that undergoes a rapid translocation to the plasma membrane in response to receptor-mediated elevation in the concentration of intracellular free Ca2+, a translocation that activates its ability to function as...