Ras-specific GTPase-activating proteinnGAPNF-1Tumor suppressor geneHPC1We report the molecular cloning of a human cDNA that encodes a molecule having striking homology with Ras-specific GTPase-activating protein
别名GAP1 like protein; MRASAL; RAS GTPase activating protein like; RAS protein activator like 1 (GAP1 like); RAS protein activator like 1; RASAL; Rasal1; rasGAP activating like protein 1; RasGAP-activating-like protein 1; RASGAP1 LIKE; RASL1_HUMAN. RAS蛋白样激活剂1抗体浓度:1mg/ml缓...
别名GAP1 like protein; MRASAL; RAS GTPase activating protein like; RAS protein activator like 1 (GAP1 like); RAS protein activator like 1; RASAL; Rasal1; rasGAP activating like protein 1; RasGAP-activating-like protein 1; RASGAP1 LIKE; RASL1_HUMAN. ...
因子2 ( Ras protein activator like 2 ,RASAL2) 、GTPase 活化 蛋白 1 ( GTPase-activating protein 1,RASA1) 、IQ 样GTPase 活化蛋 白同源体 1 ( IQ motif containing GT— Pase.activating protein homologu e 1,IQGAP1) 、IQGAP2 等,其共同特点是都含有 1 个与Ras 蛋白结合区域— — Ras...
et al. Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity. Mol. Cell. Biol. 12, 2050–2056 (1992). CAS PubMed PubMed Central Google Scholar Bollag, G. et al. Loss of NF1 results ...
RAS GTPase-activating protein (GAP) NF1 (neurofibromin 1) loss and oncogenic KRAS. Here, we show that targeting the SHP2 phosphatase (encoded byPTPN11) with RMC-4550, a small-molecule allosteric inhibitor, is effective in human cancer models bearing RAS–GTP-dependent oncogenic BRAF (for exam...
供应商: 上海田源生物技术有限公司 联系人: 杨先生 地址: 上海上海市详细信息RAS蛋白样激活剂1抗体Anti-RASAL1的产品说明:--产品介绍:Ras GTPase activating-like protein (RASAL) or RASAL1 is a member of the GAP1 family, and a Ca2+ sensor responding in-phase to repetitive Ca2+ signals by ...
产品名称:Ras GTPase-activating-like protein IQGAP1 ELISA Kit 检测范围:0.156-10 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 ...
Although they are called “GTPases,” the intrinsic GTPase activity of Ras-like proteins is rather weak, but this is stimulated by separate GTPase activating proteins (GAPs), which consequently help to hydrolyze bound GTP back to GDP, and thereby turn the GTPase off. Thus GTPases are switch...
To distinguish between inhibition of Ras by Ras GTPase-activating protein (GAP) versus a potential effector function of GAP, we tested the effector domain substitution P34R: this mutation, which abolishes GAP binding, enhanced Ras-dependent transcription in Mv1Lu cells, yet interfered with Ras-...