Amino acid sequence analysis identified the protein as IQGAP1, a recently described human Ras GTPase-activating-like protein suspected to act as an effector molecule for Cdc42 and Rac1, members of the Rho small GTPase family and to play a key part in regulating E-cadherin-mediated cell ...
产品名称:Ras GTPase-activating-like protein IQGAP1 ELISA Kit 检测范围:0.156-10 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 ...
中文名: FOR RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 ELISA KIT中文别名: FOR RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 ELISA KITCBNumber: CB38079232 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 FOR RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 ELISA KIT化学性质 ...
因子2 ( Ras protein activator like 2 ,RASAL2) 、GTPase 活化 蛋白 1 ( GTPase-activating protein 1,RASA1) 、IQ 样GTPase 活化蛋 白同源体 1 ( IQ motif containing GT— Pase.activating protein homologu e 1,IQGAP1) 、IQGAP2 等,其共同特点是都含有 1 个与Ras 蛋白结合区域— — Ras...
This protein has several interesting domains. The carboxyl terminus contains a region homologous to the RasGAP protein and the yeast protein Sar1. The central portion contains four IQ motifs that are found in many myosin-like proteins and are predicted to bind to calmodulin. The NH2 terminus ...
which bind Rho GTPases and have no GAP activity [52,53,54], IqgC is an atypical IQGAP-related protein. The GRD of IqgC retains the conserved residues essential for RasGAP activity, allowing IqgC to function as a RasGAP for the small GTPase RasG [55]. IqgC negatively regulates macro...
The Ras family of small GTPases modulates numerous essential processes. Activating Ras mutations result in hyper-activation of selected signaling cascades, which leads to human diseases. The high frequency of Ras mutations in human malignant neoplasms ha
Synonyms:ANTI-IQGAP2(C-TERMINAL) antibody produced in rabbit;IQGAP2;Ras GTPase-activating-like protein IQGAP2 CAS: MF: MW:0 EINECS: Mol File:Mol File Information Error Report Your Email: Browse by NationalityRas GTPase-activating-like protein IQGAP2SuppliersChina suppliers ...
别名:IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3 ; IQGAP3; MGC10170; MGC10831; MGC1947 antibodyOTTHUMP00000031854 ; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3; Ras GTPase-activating-like protein IQGAP3. ...
Rho GTPases can be converted to an active, GTP-bound form by guanine nucleotide exchange factors (GEFs), whereas they are converted to an inactive, GDP-bound form by GTPase-activating proteins (GAPs). Active GTP-Rho is able to bind to effector proteins, which transmit signals to downstream...