uveal melanomaRas–extracellular signal‐regulated protein kinases 1 and 2 (ERK1/2) signaling has been proposed as the crucial regulators in the development of various cancers. Histone acetylation at H3 lysine 14 (H3K14ac) is closely associated with gene expression and DNA damage. However, ...
and J.M.M. conceived drug testing and gene manipulation experiments and analyzed the data. P.v.S., M.E.E., E.L., V.C., A.B. and M.C. performed sample preparation. L.S.H., J.R., L.S., A.H., M.E.M.D. and T.F.E. contributed to in vitro drug testing and ...
75]. However, in 1999, Lee-Kirsch et al. described a new isoform of renin, Renin-b, which is exclusively expressed in the brain. Renin-b evolves from an alternative promoter within exon 1 of the renin gene resulting in the loss of a signal peptide that ...
First, we analysed the expression of the core gene RAB7A using the RNA sequencing (RNA-seq) data of PAAD samples from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases. Next, we examined the functional enrichment of RAB7A using protein‒protein interaction (PPI...
该蛋白质或潜在基因的非限制性示例性序列可在如下网页中找到:Gene Cards ID: GC12M025204(检索自/cgi‑bin/carddisp.pl?gene=KRAS,最后一次访 问日期为2021年10月9日)、HGNC:6407(检索自/data/gene‑symbol‑ report/#!/hgnc_id/6407,最后一次访问日期为2021年10月9日)、NCBI Entrez Gene:3845 (检索...
While MEN1 gene mutation is the only asce... V Corbo,I Dalai,M Scardoni,... - 《Endocr Relat Cancer》 被引量: 173发表: 2010年 Immunohistochemical analysis of nm23 gene product/NDP kinase expression in pulmonary adenocarcinoma: lack of prognostic value. Levels of nm23 gene product/...
gene features and columns denote samples (yellow, upregulated compared to median sampled; blue, downregulated expression).bDifferentially expressed transcripts were functionally and topologically analyzed by pathways and gene set analysis using IPA as described in the Methods section. The gene–gene ...
Lentiviral vectors (LVs) are attractive tools for liver gene therapy, by virtue of their ability to stably integrate in the genome of target cells and the ... A Cantore 被引量: 0发表: 2013年 Development of a liver gene therapy strategy for haemophilia B with lentiviral vectors Lentiviral ve...
Gene Ther 7: 1063–1066. [52] Barnard D, Diaz B, Clawson D, Marshall M (1998) Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms. Oncogene 17: 1539–1547. [53] Naal RMZG, Tabb J, Holowka D, Baird B (2004) In situ measurement of degranulation as...
Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice. Mol.Carcinog. 1998; 21: 251-260.Cazorla M, Hernandez L, Fernandez PL, Fabra A, Peinado MA, Dasenbrock C, et al. Ki-ras gene mutations and absence of p...