(mAbs) produced using cell lines. The main objective is to determine monoclonal cell populations producing the desired mAb with a high degree of fidelity and activity for a specific antigen. The analysis of intact biologics is continued through...
Neoself-antigen presentation in SLE: Mordred’s coronation in Arthur’s absence Mehrdad Pazhouhandeh Hongjian Sun Di Yu Research Highlights06 Jan 2025Cell Research P: 1-2 Sorting membrane proteins by size in the Golgi De Caestecker and Macara find that the sorting of membrane proteins in the ...
Their activation requires not only the direct stimulation of foreign antigens, but also the co-stimulus signal transmitted by the interaction of surface molecules.148 The CD40/CD40L pathway is one of the most important co-stimulating pathways in T-cell activation. Because of its critical role in...
protein. The E1 protein then converts to a double hexamer that encircles the DNA and unwinds the origin. The structure and function of the E1 protein is analogous to that of the polyomavirus SV40 T antigen. Much of our understanding about PV replication originates from key studies in BPV-1...
proteins or other organic molecules that fulfil similar roles as antibodies (i.e., they are able to bind antigens). Compared with antibodies, they are relatively small molecules (5–20 kDa compared with ~150 kDa) and lack complex PTMs, making them easier to produce. Chinese hamster ovary ...
leukocyte antigen-related receptor protein tyrosine phosphatases LRRTMs: leucine-rich repeat transmembrane neuronal proteins LTD: long-term depression MAPK: mitogen-activated protein kinase NCAM: neural cell adhesion molecule NLs: neuroligins Nrxs: ...
Regulator of G-Protein Signaling 16 (RGS16) (C-Term) 抗体应用备注Optimal working dilutions should be determined experimentally by the investigator. 说明 Antigen size: 202 AA 限制仅限研究用 贮存及处理 状态Lyophilized 溶解方式Add 100 µL of distilled water. ...
Recombinant Protein L contains 5 kappa-binding domain. Protein L has the unique ability to bind through kappa light chain interactions without interfering with the antibody's antigen-binding site. This gives Protein L the ability to bind a wider range of Ig classes and subclasses than other antib...
Protein vaccines are composed of purified or recombinant proteinaceous antigens from a pathogen, such as a bacterium or virus. When administered, a protective immune response is elicited against the pathogen. Latest Research and Reviews Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity...
The SpyTag/SpyCatcher protein ligation technology is valuable in many applications, but few methods exist for controlling reactivity. Here the authors report a method for controlling SpyCatcher activity via S-thiolation of engineered cysteines, demonstrating the value of their technology for the rapid ge...