iFraG A protein-protein interface prediction server based on sequence 系统标签: protein sequence interface prediction based server iFrag:AProtein–ProteinInterfacePredictionServerBasedonSequenceFragmentsJavierGarcia-Garcia1,VictòriaValls-Comamala2,EmreGuney3,4,DavidAndreu5,FranciscoJ.Muñoz2,NarcisFernandez...
The prediction methods are illustrated with two examples. Figure 7.6 shows the prediction of protein–protein interaction sites from amino acid sequence using the server, Firestar. It takes the amino acid sequence in FASTA format and displays the output with confidence levels. The prediction report ...
Proteins are the essential biological macromolecules required to perform nearly all biological processes, and cellular functions. Proteins rarely carry out their tasks in isolation but interact with other proteins (known as protein–protein interaction)
The Intrinsic Geometric Structure of Protein-Protein Interaction Networks for Protein Interaction Prediction Ramain, "The Intrinsic Geometric Structure of Protein-Protein Interaction Networks for Protein Interaction Prediction," in IEEE/ACM Transactions on Computational... Y Fang,M Sun,G Dai,... - 《...
Contains code for the paper "MaTPIP: a deep-learning architecture with eXplainable AI for sequence-driven, feature mixed protein-protein interaction prediction" explainable-ai protein-language-model deep-learning-architecture protein-protein-interaction-prediction protein-sequence-features Updated Jan 25, ...
Structural insight of the protein–protein interaction (PPI) interface can provide knowledge about the kinetics, thermodynamics and molecular functions of the complex while elucidating its role in diseases and further enabling it as a potential therapeut
and the proportion of non-interactions in each range all have an impact on the prediction performance. Given these reasons, we need to construct a reliable negative dataset, in which the degree distribution of proteins and interaction distribution are similar to those in the positive dataset. Such...
Protein–protein interactions can be seen as a hierarchical process occurring at three related levels: proteins bind by means of specific domains, which in turn form interfaces through patches of residues. Detailed knowledge about which domains and resid
Lensink, M. F. et al. Blind prediction of homo- and hetero-protein complexes: The CASP13-CAPRI experiment.Proteins87, 1200–1221 (2019). ArticleCASPubMedPubMed CentralGoogle Scholar Vreven, T. et al. Updates to the integrated protein-protein interaction benchmarks: docking benchmark version...
Sequence-based prediction of protein interaction sites with an integrative method. Bioinformatics. 2009;25(5):585–91. Article PubMed CAS Google Scholar Garcia-Garcia J, et al. iFrag: a protein–protein interface prediction server based on sequence fragments. J Mol Biol. 2017;429(3):382–9...