Proteins are the essential biological macromolecules required to perform nearly all biological processes, and cellular functions. Proteins rarely carry out their tasks in isolation but interact with other proteins (known as protein–protein interaction)
Contains code for the paper "MaTPIP: a deep-learning architecture with eXplainable AI for sequence-driven, feature mixed protein-protein interaction prediction" explainable-ai protein-language-model deep-learning-architecture protein-protein-interaction-prediction protein-sequence-features Updated Jan 25, ...
Predicting Protein-Protein Interaction Sites From Amino Acid Sequence Changhui Yan, Vasant Honavar and Drena Dobbs Artificial Intelligence Research Laborat... C Yan,V Honavar,D Dobbs - 《Engineering Applications of Computational Fluid Mechanics》 被引量: 41发表: 2002年 Prediction of Protein-Protein I...
interaction fingerprinting), a conceptual framework based on a geometric deep learning method to capture fingerprints that are important for specific biomolecular interactions. We showcase MaSIF with three prediction challenges: protein pocket-ligand prediction, protein–protein interaction site prediction ...
2.1. Computational prediction of domain–peptide interactions The biological importance of PRMs, their recognition of short simple linear motifs, and the availability of experimentally determined interaction data have prompted the development of domain–peptide interaction prediction methods by multiple groups....
The Supplementary Discussion is a comprehensive literature review of all 27 wild-type and mutant SARS-CoV-2 bait protein-protein interaction (PPI) subnetworks. Individual bait subnetwork images are provided at the front of the document for reference (and are zoomed view representations from Fig. 3...
26 Moreover, there is another hot task, drug–target interaction (DTI) prediction,27, 28, 29, 30, 31 which is similar to CPI prediction. Although both are essentially interactions between chemical compounds and proteins, their predictions are significantly different as follows. First, in terms ...
It continuously assesses the performance of automated protein structure prediction servers CAPRI The Critical Assessment of PRediction of Interactions (CAPRI) is a community-wide experiment to evaluate protein-protein interaction prediction methods PIFACE PIFACE is a web server for the prediction of ...
Structural insight of the protein–protein interaction (PPI) interface can provide knowledge about the kinetics, thermodynamics and molecular functions of the complex while elucidating its role in diseases and further enabling it as a potential therapeut
MAPE-PPI: Towards Effective and Efficient Protein-Protein Interaction Prediction via Microenvironment-Aware Protein Embedding (Spotlight) Lirong Wu, Yijun Tian, Yufei Huang, Siyuan Li, Haitao Lin, Nitesh V Chawla, Stan Z. Li. InICLR, 2024. ...