BAI Hong-Jun LAI Lu-Hua ,.Protein-Protein Interactions:Interface Analysis,Binding Free Energy Calculation and Interaction Design.[J];Acta Physico-Chimica Sinica,2010-07Bai H J, Lai L H. Protein⁃protein interactions: Interface analysis, binding free energy calculation and interaction design[ J] ...
Comparison of protein–protein interaction interface properties. (A) The overlap among interface properties that were showing statistically significant (p ≤ 0.01) differences between the native and non-native like complexes, categorized either by FNAT and iRMSD criteria. HETERO_FNAT and HETERO_i...
Protein-Protein interaction interface database (PPIIDB) is developing on the basis of cellular and biological processes of protein-protein interaction interfaces of protein network. PPIIDB is collection of dataset of PPII of Breast cancer of Homosapience which developed on the basis of various paramet...
Jones and Thornton (1997) used surface patches for predicting protein–protein interaction sites. Potapov et al. (2008) utilized molecular architecture and naturally occurring template fragments in the Protein Data Bank (PDB) for identifying protein–protein interface. The combination of sequence and ...
1) protein-protein interface 蛋白-蛋白相互作用界面2) Protein-protein interaction 蛋白质-蛋白质相互作用 1. Research progress in protein-protein interactions and their inhibitors; 蛋白质-蛋白质相互作用及其抑制剂研究进展 2. Elucidation of liver protein-protein interaction patterns will provide an ...
With SuFEx in vitro selection, we identified covalent inhibitors that cross-link distinct residues of the SARS-CoV-2 spike protein at its protein–protein interaction interface with the human angiotensin-converting enzyme 2. A separate suite of covalent inhibitors was isolated for the human complement...
Protein Protein Interaction Target:IL-17A, HeLa IC50= 5 nM Therapy Area:Inflammation Protein Protein Interaction Target:Mcl-1 Inhibitor, IC50= <3 nM Therapy Area:Oncology Small Molecules With Novel Modes Action X-Chem’s DEL platform supports the discovery of PPI modulators with unprecedented modes...
This unit offers a general overview of several techniques that have been developed for inferring functional and/or protein-protein interaction networks. Th... SM Gomez - 《Curr Protoc Bioinformatics》 被引量: 28发表: 2003年 Transient protein-protein interface prediction: datasets, features, algorithms...
This finding supports the conventional wisdom that TPSA and KOW play a key role in drug transport process46, protein interface recognition47,48, and PPI prediction49. Top outside-of-protein view improves the performance We investigate the role of top outside-of-protein view TGNN from three ...
Protein-protein interaction (PPI) leads to a stable interface for enzyme, regulatory, immune, and inhibitory function. Therefore, it is important to decipher the driving force for PPI. The principles of PPI are driven by a combination of several physical and chemical features to conserve molecular...