1996. A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent ki- nase binding and biological function, but preserves protein structure and assembly. J Mol Biol 261:646 - 657.Watson, M. H., Bourne, Y., Arvai, A. S., Hickey, M. J...
Eph and ephrin signaling is involved in many regulation processes, including axon guidance and cell migration (Davy and Soriano,2005; Xu and Henkemeyer,2012; Egea and Klein,2007). The activation of cyclin-dependent kinase 5 (Cdk5) and ephexin1 by ephrin-A1 promotes EphA4-dependent spine retra...
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These observations are consistent with ZNF827 depletion impeding normal DNA replication, resulting in failure of S phase commitment and cell cycle inhibition at G1/early S phase. DNA damage is a major inhibitor of S phase commitment, and expression of the cyclin-dependent kinase (CDK) inhibitor ...
BID BH3 interacting domain death agonist PUMA p53 upregulated modulator of apoptosis BAX Bcl-2-associated protein X BAK Bcl-2 homologous antagonist killer BFL-1/A1 Bcl-2 related protein A1 PEST proline/glutamic acid/serine/threonine CDK-1 cyclin dependent kinase 1 PCNA proliferating cell nuclear...
A. Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat interactions with both cyclin T1 and the Tat transactivation region. J. Virol. 81, 4226–4234 (2007). CAS PubMed PubMed Central Google Scholar Fulcher, A. J. et al. The protein...
P18, alias P14 should be avoided as it also refers in Homo sapiens to [76]: cyclin-dependent kinase inhibitor-2A, S100 calcium-binding protein-A9, 14-kDa replication protein-A3, catenin-β-like protein-1, CDK2-associated protein-2, SUB1 homolog, and 14-kDa subunit of splicing factor-3B...
The SNCG protein was not interacting with any of the other proteins from the pathway, yet its down-regulation occurred in more than 75% of the CRC samples. Increased expression of the SNGG gene was suggested to be a predictor of poor prognosis in esophageal or endometrial cancer patients [...
P22362 CCL1_HUMAN C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309) CCL1 SCYA1 Homo sapiens (Human) 96 Q9NYV4 CDK12_HUMAN Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell divi...
(DYRK1A,Fig. 2a) or even overlap (E1A, ref.41). It appears possible that steric hindrance by the interacting proteins in the DYRK1A/DCAF7/E1A complex shields the nuclear localisation sequences in DYRK1A and in E1A from interacting with the importin complex. The functional consequences of ...