中文名称:周期素B1蛋白英文名称:Cyclin B1 Protein 产地:国产/进口保存条件:-20℃ 纯度规格:≥96% HPLC产品类别:生物化学 用途范围:科研实验,诊断试剂规格:100ug,1mg,5mg,10mg 周期素B1蛋白,Cyclin B1 Protein 规格:100ug,1mg,5mg,10mg 来源:Recombinant/Nativemg ...
To determine whether mutations in the copper-binding sites of CDK1 cause significant alterations in protein structure or thermal fluctuations, we conducted molecular modeling analyses. The results showed that the point mutations in CDK1CBM did not significantly alter the secondary or tertiary structures...
In this article, we report the number of cyclin B1 proteins tagged with enhanced green fluorescent protein (eGFP) in fixed UOS cells across the cell cycle. We use a quantitative analysis of epifluorescence to determine the number of eGFP molecules in a nondestructive way, and integrated over ...
The cyclin B1 gene codes a protein that allows cell cycle progression through the G2/M-phase checkpoint so that mitosis occurs, and is overexpressed in some types of cancer, such as squamous cell carcinoma of the esophagus [18]. From: The Journal of Nutritional Biochemistry, 2003 ...
抗体名: 磷酸化周期素B1抗体Phospho-CyclinB1(Ser147)免疫标记 浓度: 1mg/ml % 靶点: 细胞核,细胞膜等 宿主: Rabbit、mouse 用途: 交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 应用范围: WB=1...
Cyclin B1 protein accumulates steadily through the G2 phase and associates specifically with Cdk1, although it also may associate with Cdk2.118 However, the resulting cyclin B1–Cdk1 complex is mostly sequestered in the cytoplasm, and it is retained in an inactive form throughout the G2 phase...
IP–western blot analysis indicated that ERLIN2 interacts with the key mitotic regulatory protein Cyclin B1 in the G2/M phase, but not the interphase (Figure 4a). Cyclin B1 is known to complex with Cdk1 to form M phase-promoting factor that is associated with spindle microtubules during ...
Cyclin D1,as a key protein in G1 phase, is a more sensitive indicator than other Cyclins. Herein we reviewed about the structure,function of Cyclin D1 and its expression in tumour tissue,and also preliminarily analyzed the application of Cyclin D in insect cell cycle regulation. Key words:...
Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively ...
3h) resembles the oscillatory behaviour of CDK1–cyclin B1 activity during cell division44,45 and negatively correlates with KIND2 abundance. KIND2 phosphorylation is indispensable for normal mitosis To analyse the significance of KIND2-S181 phosphorylation, we measured protein stability in ...