图5 HTRF激酶活性检测试剂盒 胞内蛋白检测试剂盒 参考文献 [1] Ardito F, Giuliani M, Perrone D, Troiano G and Lo Muzio L: The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review). Int J Mol Med 40: 271-280, 2017 ...
磷酸酶抑制剂 CocktailⅠ (100× in DMSO)含有 (-)-p-Bromotetramisole oxalate、Cantharidin 和 Microcystin LR、Microcystis aeruginosa 成分，可以有效的抑制碱性磷酸酶和丝氨酸/苏氨酸磷酸酶，用于维持蛋白的磷酸化状态。磷酸酶抑制剂 Cocktail Ⅱ (100× in ddH2O)含有 Sodium Fluoride、Sodium Orthovanadate、So...
Protein lipidation is a unique co- or posttranslational modification that plays a critical role in cell signaling, and dynamically regulates protein functions in response to extrinsic and intrinsic cues. Lipidation modulates the function of targeted proteins by increasing their binding affinity to biologic...
Protein Dynamics : From Structure to Function Chapter © 2017 Towards Molecular Movies of Enzymes Chapter © 2018 Introduction Protein functions in the cell, such as enzymatic activity, signaling, and transport, are driven by conformational changes between multiple states1,2,3. To understand bi...
ranging from rigid-body movements to liquid-like motions17,28,44,53. We observe an exponential decay of covariance as a function of interatomic distance with a scale factor of ~ 11 Å, which is consistent between force fields. This scale factor indicates that the motion in the crystal...
Engineering cell-derived extracellular vesicles for gene therapy Many genetic therapies are limited by a lack of methods for delivering them to target cells in the body. We have developed technologies to engineer biological nanovesicles to load therapeutic proteins, target recipient immune cells and deli...
Opportunities and challenges in design and optimization of protein function Dina Listov, Casper A. Goverde, Bruno E. Correia & Sarel Jacob Fleishman Nat Rev Mol Cell Biol (2024) The State-of-the-Art Overview to Application of Deep Learning in Accurate Protein Design and Structure Prediction Saber...
3 Canonical protein kinase signalling in neuroblastoma Unlike enzymes in metabolic pathways that are commissioned to turnover large amounts of substrate, protein kinases have evolved to specifically function as molecular on/off “switches” and not efficient catalysts, largely by virtue of their internal...
近日,来自复旦大学脑科学研究院和附属中山医院的杨振纲研究员团队在PNAS杂志发表了题为ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period的文章,另外,该团队在Protein & Cell杂志发表了题为BMP7 ...
产品特性This is a rabbit polyclonal antibody against RGS16. It was validated on Western Blot using a cell lysate as a positive control. 纯化方法Protein A purified 目标详细情况 别名RGS16 背景RGS16 belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increa...