Low-Dose Aspirin in the Primary Prevention of Cancer: The Women's Health Study: A Randomized Controlled Trial Basic research and observational evidence as well as results from trials of colon polyp recurrence suggest a role for aspirin in the chemoprevention of can... Nancy R Cook,I-Min Lee,...
The number can help you understand how quickly the cancer is likely to grow, and if it may spread: A number of 6 or lower means the cancer is likely to grow more slowly. A score of 7 means it is likely to grow faster, but it may not spread to other areas. A score of 8 to ...
prostate cancerprotocadherin 7SETCastrate resistant prostate cancer (CRPC) accounts for almost all prostate cancer (PCa) deaths. Aberrant activation of ERK/MEK and PI3K/AKT signaling pathways plays an important role in subsets of patients with CRPC. The role of protocadherin 7 (PCDH7) in ...
We addressed whether Gleason score 3 + 4 = 7 and 4 + 3 = 7 cancers on needle biopsy behave differently and whether this behavior is independent of the number of cores involved by cancer. If it is not an independent predictor of prognosis, one may report Gleason score 7 cancer with the...
Figure 1:Graphical representation of seven prostate cancer genomes. Each Circos plot12depicts the genomic location in the outer ring and chromosomal copy number in the inner ring (red, copy gain; blue, copy loss). Interchromosomal translocations and intrachromosomal rearrangements are shown in purple...
These studies12,13 considered age at first marriage, marital status, and number of children as measures of sexual activity and found no association between these factors and prostate cancer. Thus, the relationship between sexual activity and risk of prostate cancer is not clear....
前列腺癌 (Prostate cancer) 前列腺属于男性生殖系统,主要功能是制造与储存前列腺液。前列腺癌是全世界男性中最常被诊断出的非皮肤癌、第二常见癌症,也是男性与癌症相关的第五大死因。在美国,前列腺癌患者的五年存活率约为99%,但是肿瘤转移到了腺体外,则可能会带来更多的麻烦。因此肿瘤的检测以及控制转移是临床上意义...
Genetic testing, to identify pathogenic or likely pathogenic variants in prostate cancer, is valuable in guiding treatment decisions for men with prostate cancer and to inform cancer prevention and early detection options for their immediate blood relatives. There are various guidelines and consensus stat...
The combined number of reads of both edited and wildtype miRNAs in prostate tumor exceeds that found in non-tumor tissues. Our findings suggest that miRNA editing could not only have a significant role in the post-transcriptional regulation of cancer genes but also in the decrease of the wild...
The induction of “protective autophagy” by cancer cells is a well-known response to stress or anti-cancer drug treatment. This can be overcome by adding an autophagy inhibitor drug, such as propranolol. (DCA synergy with the autophagy inhibitor propranolol is discussed below.) In addition, Dr...