摘要: Reports on the presentation by Massachusetts General Hospital physician Michael Barry to the American Society of Therapeutic Radiation & Oncology's 2000 meeting on prostate cancer treatment. Factors in interpreting prostate cancer treatment outcome data; Side effects of treatment....
Using wholegenome analysisof plasma DNA, plus targeted sequencing of genes known to be involved in prostate cancer, the team discovered that there are abnormal copy numbers (some losses, some gains) of specific prostate cancer related sequences. Although this was a small scale study the presence ...
Dear Dr. Donohue: I am a 74-year-old man. I have not had physical exams regularly until recently. I took a pre-op exam for cataract surgery, and one of the numbers noted was for PSA. It was 6.1. I have no prostate gland symptoms other than an occasional slow urinary stream.Dr. ...
While it is widely recognized that the immune system plays a crucial role in controlling cancer initiation and progression, there has been insufficient attention given to epidemiological studies examining the link between immune status, subclinical inflammation of infectious or endogenous origin, and the ...
being the most aggressive cancer cell type. The Gleason score is based on the sum of these two numbers (tissue grade and cell type grade). A Gleason score of 5 + 5 = 10 indicates a highly aggressive prostate tumor while a low score (2 + 2 = 4) indicates a less aggressive cancer. ...
Meaning These findings suggest that a short, noncontrast MRI may have favorable performance characteristics as a community-based screening test. Abstract Importance Screening for prostate cancer using prostate-specific antigen (PSA) testing can lead to problems of underdiagnosis and overdiagnosis. Short,...
We are all human. All of us have our ego. It is only a matter of degree. Most cancer patients told me that if they asked the doctors too many questions, the doctors would become angry at them. Some doctors reacted this way –You are the doctor, or I am the doctor –meaning, if...
Meaning In patients with prostate cancer, bone metastatic burden and metastasis location may be useful in predicting survival benefit from prostate RT. Abstract Importance Prostate radiotherapy (RT) improves survival in men with low-burden metastatic prostate cancer. However, owing to the dichotomized ...
Prostate cancer lineage plasticity is a key driver in the transition to neuroendocrine prostate cancer (NEPC), and the RTK/RAS signaling pathway is a well-established cancer pathway. Nevertheless, the comprehensive link between the RTK/RAS signaling pathway and lineage plasticity has received limited ...
Meaning The single PSA screening intervention detected more prostate cancer cases but had no significant effect on prostate cancer mortality after a median follow-up of 10 years. Abstract Importance Prostate cancer screening remains controversial because potential mortality or quality-of-life benefits may...