Dear Dr. Donohue: I am a 74-year-old man. I have not had physical exams regularly until recently. I took a pre-op exam for cataract surgery, and one of the numbers noted was for PSA. It was 6.1. I have no prostate gland symptoms other than an occasional slow urinary stream.Dr. ...
Since PCa is often asymptomatic, screening for prostate cancer is essential for an early diagnosis in men above 55 years of age. PSA is the most widely used biomarker for the early diagnosis of PCa. However, the use of PSA as a screening tool for the early diagnosis of PCa has been ...
Using wholegenome analysisof plasma DNA, plus targeted sequencing of genes known to be involved in prostate cancer, the team discovered that there are abnormal copy numbers (some losses, some gains) of specific prostate cancer related sequences. Although this was a small scale study the presence ...
Existing markers for prostate cancer, such as prostate-specific antigen (PSA), have limitations in terms of sensitivity and specificity. The cost of testing, follow-up procedures, and treatment for false-positive results and overdiagnosis contributes to the overall healthcare expenditure. Improving the...
being the most aggressive cancer cell type. The Gleason score is based on the sum of these two numbers (tissue grade and cell type grade). A Gleason score of 5 + 5 = 10 indicates a highly aggressive prostate tumor while a low score (2 + 2 = 4) indicates a less aggressive cancer. ...
we created classifiers that distinguish cancer from non-cancer based solely on urine proteins; these had AUCs ranging from 0.92–1, significantly outperforming serum PSA (Fig.6b). In an independent, prospective validation cohort of 30 patients with proteomic data from all three urinary fractions (Su...
DRE should not be used as a stand-alone test for detection of prostate cancer but should be performed in men with an elevated PSA. The NCCN also notes that DRE may be considered as a baseline test in all patients, as it may help identify high-grade cancers associated with a normal PSA...
PSA down to 2.9 from 8.9 four weeks ago! Thanks for your email support and information that you gave me when my PSA was 8.9 just four weeks ago. Bill Garner (billgarner@worldnet.att.net) "Nothing I could call cancer. "These were Dr. Bard´s words to me as he scanned the power ...
Lymphatic spread determines treatment decisions in prostate cancer (PCa) patients. 68Ga-PSMA-PET/CT can be performed, although cost remains high and availability is limited. Therefore, computed tomography (CT) continues to be the most used modality for PCa staging. We assessed if convolutional neur...
WebMD's slideshow covers prostate cancer: who's at risk, symptoms, tests, staging, treatments, survival, and foods that may help lower your risk for prostate cancer.