摘要: Reports on the presentation by Massachusetts General Hospital physician Michael Barry to the American Society of Therapeutic Radiation & Oncology's 2000 meeting on prostate cancer treatment. Factors in interpreting prostate cancer treatment outcome data; Side effects of treatment....
Prostate cancer is the second most common malignancy in men worldwide and consists of a mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor microenvironment, we perform single-cell RNA-sequencing on prostate biopsies, prostatectomy specimens, and patient-derived organo...
Each prostatic lesion was assigned a score from 1 to 5 indicating the probability of clinically significant prostate cancer, as follows: PI-RADS 1: very low probability; PI-RADS 2: low probability; PI-RADS 3: intermediate probability; PI-RADS 4: high probability; PI-RADS 5: very high ...
KEY is a synthesis of my lifelong career at Prostate Oncology Specialists, a medical practice on the forefront of prostate cancer for 20 years. My first book Invasion of the Prostate Snatchers was an exposé on the over-use of surgery. This second book addresses another burgeoning problem—the ...
Dear Dr. Donohue: I am a 74-year-old man. I have not had physical exams regularly until recently. I took a pre-op exam for cataract surgery, and one of the numbers noted was for PSA. It was 6.1. I have no prostate gland symptoms other than an occasional slow urinary stream.Dr. ...
Prostate-Specific Antigen–Based Screening for Prostate Cancer: A Systematic Evidence Review for the US Preventive Services Task Force: Evidence Synthesis No. 154. Rockville, MD: Agency for Healthcare Research and Quality; 2018. AHRQ publication 17-05229-EF-1. 4. Fenton JJ, Weyrich MS, Durbin ...
provides an effective first-line treatment for advanced PCa3. Progression to lethal castration-resistant prostate cancer (CRPC) is common and accompanied by restoration or maintenance of AR signalling, which is involved in the regulation of metabolism4,5, cell cycle checkpoints6and DNA repair7,8,...
Although prostate cancer (PCa) is the most common cancer type in men, a replaceable risk factor has not yet been established. In our study, we assessed the relationship between the number of sexual partners, age of first sexual experience and age of first masturbation and prostate cancer incide...
3. When Johnny was down with cancer, the family’s first priority was to seek medical help. Johnny was sent to a well-known hospital in Kuala Lumpur for treatment. We respected that decision.Go ahead and see what the doctor can offer you!
Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent. Expression of constitutively active AR variants lacking the ligand-binding domain including...