A facility, method and system for producing a therapeutic protein comprises the steps of collecting eggs from transgenic birds in a production unit in a building; transferring eggs to a collection unit in a building; and transferring eggs To recover egg white or egg yolk.パシェク アダム ア...
Biotechnological production of high-value metabolites and therapeutic proteins by plant in vitro systems has been considered as an attractive alternative o... MI Georgiev,R Eibl,JJ Zhong - 《Applied Microbiology & Biotechnology》 被引量: 85发表: 2013年 Scale up studies for the production of biosur...
1536Citations 42Altmetric Metrics Abstract Cultivated mammalian cells have become the dominant system for the production of recombinant proteins for clinical applications because of their capacity for proper protein folding, assembly and post-translational modification. Thus, the quality and efficacy of a ...
biomass is accumulated prior to protein expression. Therefore, cells are not stressed by the accumulation of recombinant protein during growth phase, and even the production of proteins that are toxic toP
(UPR) is initiated to restore homeostasis in response to ER stress, and optimization of the UPR can improve CHO cell production of therapeutic proteins. We compared the fed-batch growth, production characteristics, and transcriptomic response of an immunoglobulin G1(IgG1) producer to its parental,...
Toxicity profile of the investigational new biotherapeutic agent, B43 (anti-CD19)-pokeweed antiviral protein immunotoxin. The investigational biotherapeutic agent, B43(anti-CD19)-pokeweed antiviral protein (PAP) immunotoxin, has shown substantial anti-leukemic activity in SCID... R Gunther,LM Chelstro...
Peptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicamentPeptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicamentThe invention relates to peptides or proteins of general formula (I), where R1 and...
has been utilized for cheese production, and for the past 3000 years, soy sauce in Asia and bread in Egypt represented examples of traditional fermentations.1 Natural products from microbes have a broad range of therapeutic applications and are often produced via primary or secondary metabolism. ...
those fromE. coli[44–47], phages [48,49], and virus [50]. Soon after, the attention for this expression system broaden to other proteins of biotechnological interest, in particular for the production of human therapeutic recombinant protein such as β interferon, insulin, recombinant human ...
STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells This combined effect of STAT3 inhibition/depletion and anthracyclines was only found in tumors growing on immunocompetent (not in immunodeficient) mice. As ... Heng,...