BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system (p 662-669) , Varma S, Jacob R, Kuo LE, Shooter EM (2004) BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system... Ravi,J.,Tolwani,... ...
Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis A major question in neurobiology is whether myelin repair can restore neurological function following the course of a severe, progressive CNS demyelinating... PD...
The number of polyribosomes in the perikarya and cell processes was greatly reduced and the rough endoplasmic reticulum was disorganized. Mitochondria and microtubules were normal in appearance. Many oligodendroglial tongue processes at the inner margin of the myelin sheath were enlarged, occasionally ...
Anti-SFV antibodies generated during SFV infection may affect CNS function due to cross-reactivity with a peptide of oligodendrocyte myelin glycoprotein. To explore this possibility, total IgG from SFV immunized or normal control rabbits was unilaterally microinfused into the subthalamic region of normal...
Glial cytoskeleton reorganization, oligodendrocyte differentiation and myelin ensheathment (MBP,MOBP,PLP1,MAG,ZNF488) were downregulated. The data sets were confirmed by real-time PCR. These viral defense-signaling patterns paralleled neuroimmune communication networks seen in HIV-1-infected human brains....
Further, ODC that overexpress CNP appear to mature earlier in development, resulting in earlier maximum gene expression for myelin basic proteins and proteolipid protein. These results indicate that CNP is an early expressed regulator of cellular events that culminate in CNS myelination. 展开 ...