Scherer SS, Arroyo EJ (2009) Myelin: molecular architecture of CNS and PNS myelin sheath. In: Larry RS (ed) Encyclopedia of neuroscience. Academic, Oxford, pp 1169–1180Scherer S S,Arroyo E J.Myelin:molecular architecture of CNS and PNS myelin sheath.Encycl Neurosci. 2009...
In the central nervous system (CNS), oligodendrocytes (OLs) are responsible for the production and maintenance of the myelin sheath. OLs originate from oligodendrocyte precursor cells (OPCs), which arise in the embryonic (ventral OPCs) and perinatal (dorsal OPCs) mouse telencephalon in distinct s...
Schwann cells and oligodendrocytes make the myelin sheaths of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. Their myelin sheaths are structurally similar, consisting of multiple layers of specialized cell membrane that spiral around axons. Both kinds of myelin shea...
The CNS of the mutant mld has a severe myelin deficit. In contrast, myelination is normal in the PNS. Previous studies showed that myelin basic proteins (MBP) are practically missing in mld CNS and PNS tissues. Using an in vitro system and immunoprecipitation, we present evidence that MBP sy...
Myelin is formed as an extension and modification of the surface membrane of the oligodendrocyte in the central nervous system (CNS) and the Schwann cell in the peripheral nervous system (PNS). The extended plasma membranes are wrapped around the axons in a spiral fashion, leading to a structur...
systems. The sheath is formed by the wrapping of multiple layers of the cellular membrane (mainly lipoprotein) of the myelin-producing cells around the axon. In the central nervous system (CNS) these cells are theoligodendrocytes, and in the peripheral nervous system (PNS) these cells are...
Specialized glial cells—oligodendrocytes in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS)—form myelin by repeatedly wrapping axon segments. Debilitating diseases result from the disruption of myelin, including multiple sclerosis and Charcot-Marie-Tooth ...
Myelin is formed as an extension and modification of the surface membrane of the oligodendrocyte in the central nervous system (CNS) and the Schwann cell in the peripheral nervous system (PNS). The extended plasma membranes are wrapped around the axons in a spiral fashion, leading to a structur...
作者: F.,Lin,Tai,and,Ross,Smith 摘要: The relationship between the proteins of shark central nervous system (CNS) myelin and those of myelin from higher classes has been investigated using antibodies raised against a 31,500 molecular weight polypeptide from shark myelin. The antibodies cross-...
How are nerve signals propagated along axons and between different neurons? What is the difference in the repairs in CNS (central nervous system) versus that in PNS (peripheral nervous system)? When the K-channels in the axon open, what would happen? a. depolarize the neuron b. block...