Proapoptotic genes BAX and CD40L are predictors of survival in transitional cell carcinoma of the bladder. Br. J. Cancer, 88(4):586-592. [doi:10.1038/sj.bjc.6600765]Hussain SA,Ganesan R,Hiller L,et al.Proapoptotic genes BAX and CD40L are predictors of survival in transitional cell ...
如此告诉我为什么不长期,在我得到了工作之后,杰里米・林进来得到某些信奉瑜伽者我发誓我的时间关闭![translate] aon the promoters of pro-apoptotic genes, 在赞成apoptotic基因的促进者,[translate]
unnecessary apoptosis; Phase 2: in response to continuous and severe DNA damaging stresses when apoptosis is required to discard severely dam- aged cells, TFIIS.h is induced and accumulated by continuously activated p53 to rescue the transcription elonga- tion arrest of apoptotic genes, such as ...
Thus, diabetes-enhanced apoptosis represents an important mechanism through which healing is impaired, and this can be explained, in part, by diabetes-increased expression of proapoptotic genes and caspase activity. 展开 关键词: Diabetes DOI: 10.2337/diabetes.55.02.06.db05-1201 ...
miR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer's model.AbstractAlzheimer's disease (AD), an age-related progressive neurodegenerative disorder, exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the ...
In summary, SIVA is a proapoptotic gene that is expressed in a broad scope of tissues, including cells of the immune system, tumor cells, and in the CNS. SIVA is induced in response to p53 and E2F1, two tumor suppressor genes that function in cell cycle regulation and apoptosis. Up-regu...
Transcriptional activation of pro-apoptotic genes in response to cytotoxic stimuli is a conserved feature of the cell death pathway in metazoans. However, understanding the extent of this conservation in insects has been limited by the lack of known pro-apoptotic genes in non-drosophilids. Recently...
PNAS-4, a novel pro-apoptotic gene, was activated during the early response to DNA damage. Our previous study has shown that PNAS-4 induces S phase arrest ... Y Zhu,W Guo,J Yang,... - 《Journal of Biological Chemistry》 被引量: 16发表: 2015年 加载更多来源...
pro-apoptotic genes such as Caspase 7 and p73,13 and that RB/E2F-1 is a major contributor of Noxa induction in response to ABT-737 treatment, a Bcl-2 inhibitor.48 Thus, pRb/E2F proapoptotic signaling(s) can be activated in response to oncogenic stress, DNA damage or Bcl-2 inhibition....
Given the multiple links between the NF-kB and apoptotic signalling pathways, we have analyzed here the structure, regulation and function of IKIP. Results Identification of IKIP and localization to APAF1 Initially, we performed yeast two-hybrid screens to identify novel genes involved in the NF-...