1997. Effect of anti-apoptotic genes and peptide inhibitors on cytoplasmic acidification dur- ing apoptosis. FEBS Lett. 411:67-70.Pardhasaradhi, B. V. V.; Khar, A.; Srinivas, U. K. Effect of anti-apoptotic genes and peptide inhibitors on cyto- plasmic acidification during apoptosis. FEBS ...
105 mediates activation of anti-apoptotic genes by NF-?B doi:10.1093/emboj/17.17.5161GENESNUCLEOTIDE sequenceIMMUNE responseVIRUS diseasesRNACELLULAR immunityThe transcription factor NF-κB is important for expression of genes involved in immune responses, viral infections, cytokine ...
The major challenge in treating cancer is that many tumor cells carry mutations in key apoptotic genes such as p53, Bcl family proteins or those affecting ... SP Cregan,VL Dawson,RS Slack - ONCOGENE -BASINGSTOKE- 被引量: 0发表: 2004年 Caspase-independent cell death: leaving the set without...
In the past ten years, a tremendous amount of work has demonstrated that enhanced cell proliferation caused by activation of oncogenes or inactivation of tumor suppressor genes is one of the major causes of human cancer. However, recentl... X Yang - 《Memorial University of Newfoundland》 被引...
The results of RT-PCR indicated that the specific bands of the amplified product by PCR were close to the expected sizes of the Bag-1 and Bcl-2 genes. Higher expressions of Bag-1 and Bcl-2 genes were discovered in the colon carcinoma tissues. However, they were not observed in the norm...
The aims of this study were to investigate the expressions and significance of the antiapoptotic genes Bag-1 and Bcl-2 in colon cancer and to evaluate their relationship. The expressions of Bag-1 and Bcl-2 were examined in 128 colon cancer and 20 normal colon tissue samples by reverse-transc...
The expanding wealth of human, model and other organism's genomic data has allowed the identification of a distinct gene family of apoptotic related genes... Lan,Hu,Temple,... - 《Apoptosis》 被引量: 80发表: 2009年 Sequence analysis shows that Lifeguard belongs to a new evolutionarily conserv...
The anticancer activity of the NPs was assessed against breast cancer cell lines, and the expression of pro-apoptotic and anti-apoptotic genes was evaluated using quantitative real-time reverse transcription polymerase chain reaction (PCR); however, their apoptotic and cell cycle arrest potential were...
Furthermore, we found that during TNF-alpha stimulation, NF-kappaB-regulated anti-apoptotic genes were upregulated in HepG2 cells but were downregulated in HepG2.2.15 cells. Based on the previously mentioned results, we can conclude that the IKK-p-level changes induced by HBV infection modulate...
(TNFR1) and several other stimuli.1,2 Although the mechanisms by which anti-apoptotic genes that are regulated by NF-kB inhibit TNF-induced apoptosis remain to be fully explored, it has been well established that the anti-apoptotic function of NF-kB downstream of TNFR1 involves suppression of...