He was found to have elevated serum alkaline phosphatase activity and work up revealed primary biliary cholangitis. This case highlights the importance of workup for chronic liver disease as the elevated serum alkaline activity may be mistakenly attributed to bone, especially in geriatric population....
Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Recommendation 1: The presence of isolated AMA positivity with normal serum liver tests is not sufficient to make the diagnosis of primary biliary cholangitis. However, in consideration of the potential for disease progression, these patients should be monitored on an annual basis with liver biochemist...
Biliary Cystadenocarcinoma: A Rare Tumor of the Liver A 55-year-old woman was admitted to our hospital for the workup of a cystic multilocular tumor of the left lobe of the liver. She underwent a left lobectom... Barthet M.,Garcia T.,Payan M.J.,... - 《Dig Surg》 被引量: 3发...
Ultrasound examination of the liver and biliary tree is obligatory in all cholestatic patients in order to differentiate intrahepatic from extrahepatic cholestasis. When the biliary system appears normal and serum AMA are present, no further radiologic workup is necessary. Abdominal lymphadenopathy, particu...
Ba-Ssalamah, Diagnostic workup of primary sclerosing cholangitis: the benefit of adding gadoxetic acid-enhanced T1-weighted magnetic resonance cholangiography to conventional T2-weighted magnetic resonance cholangiography, Clin Radiol 69(5) (2014) 499-508. https://doi.org/10.1016/j.crad.2013.12.008...
interruption of KEYTRUDA (≥2%) were decreased neutrophil count (18%), decreased platelet count (10%), anemia (6%), decreased white blood cell count (4%), pyrexia (3.8%), fatigue (3.0%), cholangitis (2.8%), increased ALT ...
She was diagnosed with autoimmune hepatitis-primary biliary cholangitis overlap syndrome1 with hepatic encephalopathy. She was treated with steroids with full resolution of her myoclonus (Video 1, part 3). Hepatic encephalopathy is usually associated with negative myoclonus (asterixis) rather than reflex...
BILIARY tractNEUROENDOCRINE tumorsLIVER transplantationENDOSCOPIC ultrasonographyCAPSULE endoscopyCHOLANGITISBackground: Neuroendocrine tumors (NETs) are rare epithelial neoplasms that arise most commonly from the gastrointestinal tract. In pediatrics, the most common site of origin is in the appendix, with the...
Primary sclerosing cholangitis (PSC) is a rare, idiopathic, and complex disease entity that affects both intrahepatic and extrahepatic biliary ducts. The exact cause of this disease is not known; however, it may be due to an autoimmune process due to its link to ulcerative colitis. PSC is a...