UK-PBC:STRATIFIED MEDICINE IN PRIMARY BILIARY CHOLANGITIS ABOUT UK-PBC PROJECTABOUT PBC DISORDER About UK-PBC is a unique collaboration between patient groups, doctors, scientists and industry with a shared interest in increasing understanding about, and treatment for the autoimmune liver disease Primar...
Primary biliary cholangitisCase findingOntologyPrimary careSecondary careIntroductionPBC registries in the UK focus on data from secondary care without clear coordinated contribution from primary care. The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) receives data from...
原发性胆汁性胆管炎(primary biliary cholangitis, PBC) 前言:原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其...
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其病变由自身免疫异常引起,最终可能进展为肝硬化和肝衰竭,该病具有遗传倾向。本文主要的参考文献为中华医学会肝病学分会《2021原发性胆汁性...
You’ve probably never heard of the chronic liver condition primary biliary cholangitis (PBC) before – but 25,000 people in the UK are living with it
Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
Primary biliary cholangitis (PBC), formally known as primary biliary cirrhosis, is a chronic cholestatic liver disease that predominantly affects adult women of all ages, more commonly in the middle years of life. It presents as a chronic nonsuppurative destructive cholangitis with granuloma formation...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well-orchestrated immune reaction, both innate and adaptive, against mitochondrial antigens that specifically targets intrahepatic bi...
Primary biliary cholangitis 来自 学术范 喜欢 0 阅读量: 77 作者: P Albert 摘要: Primary cholangitis (cirrhosis) is a chronic cholestatic disease with an unquestionable female predominance. It is characterised by inflammation of the small and medium size bile ducts, and can eventually progress to ...
Pruritus affects up to 80% of patients with primary biliary cholangitis (PBC) and reduces health-related quality of life (HRQoL). GLIMMER (NCT02966834) was a randomized, placebo-controlled phase IIb study of linerixibat in patients with PBC and pruritus. Using patient-reported outcome data from...